Hopefully, we start winning the vets over when they see the results, and they 
start to tell each other about some success for FeLV cats with this 
combination. By the way, I have also effectively used this combination for a 
cat who, I believe had FIV, and I currently am using just the Doxy/Winstrol 
combination on 2 of 3 kittens we picked up from the side of the road in August 
and they displayed the symptoms of Lyme Disease (alternating lameness and other 
signs). In the last case, I am pretty sure that the majority of the effect on 
the Lyme organism (Borrelia bergdorferi) is from the Doxycycline, but the good 
effect on the lameness (which had been in place for several months before I 
thought to try the medications) is I believe as a result of the use of the 

When the vets tell me that (a) they don’t know what the diagnosis is and other 
options seem ineffective or (b) they tell me there is no hope, I will usually 
try the Winstrol and almost always get a decent result.


From: Felvtalk [mailto:felvtalk-boun...@felineleukemia.org] On Behalf Of Randy 
Sent: January-22-17 11:54 AM
To: felvtalk@felineleukemia.org
Subject: Re: [Felvtalk] Curly's gradual improvement

Amani, you asked what our vet thought about Curly's improvement. He was very 
pleased but I think he was also a little surprised. He is an incredible vet and 
always goes the extra mile to listen and explain things. He was also very open 
to letting us try the Prednisolone, Doxy and Winstrol, even though he'd never 
treated a FELV cat in that way. I think he thought it would help put my mind at 
ease that we'd tried everything we could and he's right. It would have done 
that even if the treatment hadn't worked. He was very concerned about the 
Prednisolone opening her up to secondary infections but once he saw the numbers 
start to improve he was convinced we were doing the right thing and told us to 
keep it up. I am going to talk to him about continuing the Doxy.
Robert, that's a great idea about crushing the Doxy, mixing it in broth and 
administering with a syringe. We'd tried mixing it in her food once and that 
did not go well. Obviously it's a very nasty tasting medicine.
Ardy and Katherine, thanks for your support. I really wish that more vets were 
open to trying novel treatments that hold so much potential instead of assuming 
that they know everything.

On Thu, Jan 19, 2017 at 9:11 PM, Amani Oakley 
<aoak...@oakleylegal.com<mailto:aoak...@oakleylegal.com>> wrote:
Oh Randy, I am so THRILLED to hear of your positive response to the 
medications, and that your vet was so helpful. (What does your vet think of the 
response?) You may think that 15% haematocrit is still very sick, and it is 
still well outside the normal range, but you’ve basically had a 60% increase in 
haematocrit in 3 weeks. That is quite amazing and wonderful. It is as good a 
result as you would have had with 2 units of blood being given as a 
transfusion, only it is much better than a transfusion because Curly is 
producing her own cells, rather than temporarily filling up with someone else’s 

With respect to the Doxy, I am not sure. If it were me, I would probably want 
to continue if you can. You’ve had a very good result. Why mess with the 
formula? I can’t say definitively, one way or the other, since I very much 
figured things out by running weekly blood work and if I saw a dip or a 
reversal in the numbers, I would adjust the medication accordingly. I don’t 
know if I am right about my Doxy theory (and it is just pure conjecture on my 
part, based on my non-vet research) but I really think that the Doxy is part of 
the effective package. I feel that the Doxy holds the virus in check – perhaps 
slowing down its reproduction by inhibiting RNA synthesis – enough to allow the 
body to make some progress with the Winstrol. I don’t think that the Winstrol 
on its own is enough.

With the Doxy, I used to scrape the quarter tablet into a slab of butter to 
coat it with butter, to help it slide down better, since the quarter table it 
very dry and scratchy. I also posted recently that the Doxy we get from vets 
(and even from our doctors) is the same as what you can get to treat fish or 
birds, in a pet store, and that is sold in powdered packages of 100 mg (same as 
1 tablet). A prescription isn’t needed for it, and because it is powdered, it 
can be mixed into food or liquid.

Great news, too, with your success in getting her to eat more and put on weight.

I love to hear good news on this front. Let’s hope she continues in the right 


From: Felvtalk 
 On Behalf Of Randy Henke
Sent: January-19-17 9:53 PM
To: felvtalk@felineleukemia.org<mailto:felvtalk@felineleukemia.org>
Subject: [Felvtalk] Curly's gradual improvement

It has been a little over a month ago that I asked for advice on this forum for 
our little girl, Curly.
At that point, I had little hope. She was so lethargic and her hematocrit had 
dipped to a critical 9%. I took everyone's advice, especially Amani's, and 
asked our vet for Predisolone, Winstrol and Doxycycline.
According to her latest CBC two weeks ago, she is still a very sick kitty but 
her hematocrit rebounded to 15% which I know is still very low. All other 
numbers are improving slowly as well. That was after less than three weeks of 
She is due for another CBC next Tuesday and I am hopeful we will see more 
improvement. I've noticed her gums are more pink which I believe is a good sign.
We were still having problems with getting her to eat. She would have her good 
days and her bad days but her weight was still creeping down. Last week I asked 
our vet about Mirtazapine and our vet agreed to give us a prescription for it. 
I have to thank Robert for mentioning this in one of his posts.

One day last week she didn't want to eat so I gave her a quarter pill (3.75 mg) 
which is the dose our vet prescribed to give her daily. The result was 
phenomenal and almost a little scary. She was bouncing off the walls within a 
few hours and eating everything she could get her paws on. I almost felt a 
little sorry for her because it was like she couldn't sit still for more than a 
couple of minutes. But it was like getting our old Curly back again in just a 
single day!
The effect tapered off after a couple of days and we didn't feel comfortable 
giving her another dose until she stopped eating again because of how dramatic 
the change was. I've read online that a smaller dose could be effective if 
given every 72 hours so we are going to try doing that so she keeps eating. It 
was incredible to see her weight go up by a quarter pound in just a couple of 
We are continuing the Prednisolone and Winstrol at the recommended doses but 
our two week Doxycycline prescription ran out over a week ago. She does appear 
to still be making improvement without it but I'm wondering if I should ask for 
another prescription to keep that going as well.
I always worry about giving her the quarter pill of Doxy because I know it can 
cause esophageal damage if it isn't followed by liquids. I was following the 
pill with the liquid Winstrol solution but wasn't sure if that was enough.
Many thanks to everyone who gave us advice. It looks like we might have our 
Curly back for at least a while yet and it's all because of you people.

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