Ardy - there are a number of publications which deal with the mode of action of 
Doxycycline and its antiviral properties. It doesn’t kill the virus but 
inhibits its replication, sometimes by interfering with cell wall development 
and other times by preventing the virus from penetrating cells. Viruses usually 
replicate by invading a normal host cell, taking over its "machinery" and 
basically getting the host cell to make millions more viruses, which are then 
released into the circulation when the cell bursts. Doxycycline has been shown 
to sometimes inhibit the penetration of the virus into the cell.

So for example, Doxycycline has been found to be effective against Dengue 
fever. There are a number of publications exploring the effectiveness with 
Dengue fever. Here is an excerpt from a 2014 publication from the Archives of 
Virology (Inhibitory Effect of Doxycycline against Dengue Virus Replication in 
Vitro):

"Doxycycline is an antibiotic derived from tetracycline that possesses 
antimicrobial and anti-inflammatory activities. Antiviral activity of 
doxycycline against dengue virus has been reported previously; however, its 
anti-dengue properties need further investigation. This study was conducted to 
determine the potential activity of doxycycline against dengue virus 
replication in vitro. Doxycycline inhibited the dengue virus serine protease 
(DENV2 NS2B-NS3pro) with an IC50 value of 52.3 ± 6.2 μM at 37 °C (normal human 
temperature) and 26.7 ± 5.3 μM at 40 °C (high fever temperature). The antiviral 
activity of doxycycline was first tested at different concentrations against 
DENV2 using a plaque-formation assay. The virus titter decreased significantly 
after applying doxycycline at levels lower than its 50 % cytotoxic 
concentration (CC50, 100 μM), showing concentration-dependent inhibition with a 
50 % effective concentration (EC50) of approximately 50 μM. Doxycycline 
significantly inhibited viral entry and post-infection replication of the four 
dengue serotypes, with serotype-specific inhibition (high activity against 
DENV2 and DENV4 compared to DENV1 and DENV3). Collectively, these findings 
underline the need for further experimental and clinical studies on 
doxycycline, utilizing its anti-dengue and anti-inflammatory activities to 
attenuate the clinical symptoms of dengue virus infection."

Doxycycline has also been found to be effective against West Nile virus, 
reovirus, Japanese encephalitis virus (JEV), vesicular stomatitis virus (in 
vitro), mural virus (a mouse virus which causes leukemia in mice), and more. 
Doxycycline is also effective against more unusual organisms like protozoa (eg 
- malaria) and the unusual bacteria which cause Lyme Disease and Rocky Mountain 
Spotted Fever.

Unbelievably, Doxycycline has also been shown to suppress metastatic cancer or 
assist in bone metastatses. I suspect this last finding is not a strong one 
since I don’t know that Doxycycline is routinely used for this. However, I sure 
wish I had known this when my family member was suffering from cancer. Again, 
under the category of "it might not do a darn thing but it's unlikely to be 
worse than the situation you're facing", I would have given this a try. There 
are quite a few publications looking at the use of Doxy for cancer though, so I 
think there is probably something there.

I doubt that anyone is studying the effect on the Feline Leukemia virus because 
I see little research involving cat conditions generally, and even less focused 
on the Feline Leukemia virus. I obviously went looking for an explanation as to 
why Doxycycline and Winstrol might have been effective with Zander, because I 
too had the general understanding that antibiotics are not effective against 
viruses (and I have a Microbiology degree!). I suspect that most physicians and 
vets have also had this "rule of thumb" hammered into their heads. It is 
generally true of course, but it obviously works to create a blind spot for 
physicians and vets, when it comes to the "exceptions" to this general rule. 
Also, what I have also come to understand is that when there is a drug like 
Doxycycline (and Winstrol), which has been around for a long time and the drug 
companies no longer have a patent on it, they can't make money on it, so they 
stop doing any research related to it. They focus their research on their new 
drugs on which they hold patents, so they can push these, and make more money.

And don’t even get me started on cannabis oil. To imagine where society might 
have been if we'd focused on researching the effects of cannabis on everything 
from cold sores to cancer for the last 100 years, is to truly despair at the 
sheer stupidity and duplicity of governments and certain people with devious 
designs. Oh, and cannabis' entirely benign cousin - hemp - which got swept into 
the ban for no legitimate reason at all - is able to be used for everything 
from a food source, to clothing, to fertilizer, to flooring, to automobile 
manufacturing, to building materials, to making non-toxic and biodegradable 
plastics AND A NONTOXIC ALTERNATIVE TO PETROCARBONS. (For a mind-blowing 
exercise, look up Henry Ford's first car made of hemp!) 

The more we learn, the more sad the picture gets. However, just maybe this 
Internet thing will allow us not to be so easily manipulated by our leaders 
(one hopes). 

Amani  
 
-----Original Message-----
From: Felvtalk [mailto:felvtalk-boun...@felineleukemia.org] On Behalf Of Ardy 
Robertson
Sent: June-24-17 9:36 AM
To: felvtalk@felineleukemia.org
Subject: Re: [Felvtalk] Lysine

Thanks Amani - I am also very intrigued by Doxycycline being able to, I believe 
you said - possibly stop the FeLV virus from replicating. Is this being studied 
and tested by vets, schools, etc.?

I also through it was said that the cannibas oil stopped the herpes virus of 
cold sores - my word - I thought we had nothing to defeat viruses. Docs always 
say "it's a virus, it has to run its course" - well maybe not! Yet they aren't 
looking at obvious sources just because of its third cousin - "weed". Good 
grief!

Rant over!
Ardy


-----Original Message-----
From: Felvtalk [mailto:felvtalk-boun...@felineleukemia.org] On Behalf Of Amani 
Oakley
Sent: Friday, June 23, 2017 11:16 PM
To: felvtalk@felineleukemia.org
Subject: Re: [Felvtalk] Lysine

Ardy, I think it was precisely because of my experience with Winstrol that I 
was open to the unthinkable thought that science and scientists weren’t always 
free to produce unbiased research, even when it could help a lot of animals or 
people.

I am, first and foremost, a scientist by training and inclination, and this 
concept was terribly foreign to me when I first stumbled upon the bizarre 
Winstrol situation. 

Amani

-----Original Message-----
From: Felvtalk [mailto:felvtalk-boun...@felineleukemia.org] On Behalf Of Ardy 
Robertson
Sent: June-24-17 12:12 AM
To: felvtalk@felineleukemia.org
Subject: Re: [Felvtalk] Lysine

Sort of like the stigma surrounding Winstrol due to the misuse of it by an 
Olympic athlete....... people and animals who could be helped by it are not. 
People are crazy sometimes.

Ardy

-----Original Message-----
From: Felvtalk [mailto:felvtalk-boun...@felineleukemia.org] On Behalf Of Amani 
Oakley
Sent: Wednesday, June 21, 2017 12:42 PM
To: felvtalk@felineleukemia.org
Subject: Re: [Felvtalk] Lysine

Cannabis is an absolutely amazing product. Do your own research. You will see 
very solid scientific evidence that backs up the many positive effects this 
substance has. In fact, I was pretty enraged when I did the research. It is 
clear that the decision to ban this substance was fraught with racial 
overtones, and was introduced simply because after the demise of prohibition, 
the government agency tasked with enforcing prohibition, needed a new mandate. 
It is also appalling that because of this ill-conceived war on drugs, and 
placing cannabis on Schedule 1 in the United States, virtually all scientific 
testing was either banned completely, or faced so many obstacles, that most 
scientists avoided doing any research on it at all. Thus, much of the 
scientific studies come from Spain and Israel. Oddly enough, when a 
pharmaceutical company decided to extract one of the key substances from the 
cannabis plant and market it as Marinol, it suddenly went from having no known 
medicinal qualities (the criteria to have it listed in Schedule 1) to being a 
very effective drug which can be marketed and can make lots of money for the 
drug company.

Do your own research. There is tons of stuff on the internet. There are Harvard 
professors and top-notch researchers turning out excellent, amazing research 
regarding the healing powers of this substance.

Oh, and the reason why so many of the States are now recognizing it for its 
medicinal qualities and legalizing it, is because it is unbelievably effective 
in helping young children suffering from severe forms of epilepsy where they 
literally convulse hundreds of times an hour, and the only medications 
heretofore even slightly effective would put these children into complete 
zombie states. Cannabis not only relieves the unbearable non-stop seizures, but 
doesn’t affect the children's level of consciousness. Parents in states which 
have not legalized marijuana have literally moved their whole families to other 
states to access medical marijuana when they have children suffering these 
syndromes. Even Republicans have in some instances been moved to back bills 
legalizing medical marijuana, when they have been confronted with these 
suffering children. Medical marijuana has also been found to be very effective 
for PTSD states, such as those suffered by servicemen and women who have served 
overseas and have witnessed traumatic events. 

With respect to cancer therapy, one of the worst cancers is the glioma which 
occurs in the brain. With such a diagnosis, most patients were dead within 6 
months. Spanish researchers have recently shown that in mice with 
experimentally-induced gliomas, and treated with cannabinoids, 1/3 showed 
complete resolution of the glioma, 1/3 showed a standstill in the development 
of the glioma, and 1/3 showed no improvement. Given that nothing else has been 
found to be consistently helpful in treating gliomas, these results are nothing 
short of earth-shattering. 

Read and learn. I cry when I think of all the people who might have been helped 
if not for the conspiracy related to this drug. It is deeply deeply disturbing.

Amani

-----Original Message-----
From: Felvtalk [mailto:felvtalk-boun...@felineleukemia.org] On Behalf Of 
dlg...@windstream.net
Sent: June-21-17 4:26 AM
To: felvtalk@felineleukemia.org
Cc: ROBERT CHAPEL
Subject: Re: [Felvtalk] Lysine

I agree on the cannibinol.  I wonder if maybe some of this is to justify making 
it legal saying it is for medical reasons.  It can't be all that wonderful, 
nothing is and when someone tells me that, I get suspicious.

---- ROBERT CHAPEL <bcha...@optonline.net> wrote: 
> 


Amy....
I'm not able to link to the article simply because it was not something I held 
on to...  At the time I had two FeLV+ young cats and I did NOT want to hear 
that one of the few things that I COULD do for them was useless....  I 
mentioned it to a couple of vets who were rather insistent that it IS 
useful....  Yes/No Maybe so  : )  I chose to believe and did not make a point 
of keeping the article for reference...  and Amani ( if you happen to read 
this)  I am getting hopeful about all of the uses of cannabinol ( though I AM 
suspect when something is said to be useful for everything from Cancer to 
Transmission Trouble in Oldsmobiles)...  With all the Hoopla there must be a 
pony in there somewhere..

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