Hi Katrin, You'll have to take the natural logarithm of your DVs I would change your error block to:
$ERROR IPRED=LOG(F+1E-16) ; Protection against LOG(0) in case of dosing events etc Y=IPRED+ERR(1) ; FOR PROPORTIAL ERROR Cheers! Rob Van: owner-nmus...@globomaxnm.com [mailto:owner-nmus...@globomaxnm.com] Namens Katrin Volz Verzonden: vrijdag 16 december 2016 10:35 Aan: nmusers@globomaxnm.com Onderwerp: [NMusers] $Error log transformed Dear All, I would like to model my data log transformed. So far, I already found some suggestions for this problem here but none of them worked in my case - probably I did sth. wrong. I would be very happy if someone could help me with changing my error model, which I assume has to be changed. (I also assume that the dataset has to be changed from DV to LOG(DV)?) So, here is the code I used so far (not log transformed): $ERROR IPRED = F ;IPRED drug in the central compartment IF (CMT.EQ.5) IPRED = A(5) ;IPRED second drug in 5th compartment DEL=0 IF (IPRED.EQ.0) DEL=0.0001 W = F IRES = DV - IPRED IWRES = IRES /(W + DEL) Y = IPRED + IPRED * EPS(1) ; error drug in the central compartment IF (CMT.EQ.5) Y = IPRED + IPRED * EPS(2) ; error second drug in 5th compartment It would be great to get some help. Thanks! Katrin Het Radboudumc staat geregistreerd bij de Kamer van Koophandel in het handelsregister onder nummer 41055629. The Radboud university medical center is listed in the Commercial Register of the Chamber of Commerce under file number 41055629.
