Colleagues,
A tutorial "R-based reproduction of the estimation process hidden behind NONMEMR Part 2: First-order conditional estimation" by Prof. Kyun-Seop Bae was published to Transl Clin Pharacol 2016;24(4):161-168 weeks ago. Previously, he published the same topic on the FO method. (Transl Clin Pharacol 2015;23:1-7). These tutorials let you learn how NONMEM calculates objective function values through step-by-step reproduction using the R codes written by the author. You may find a copy of the tutorial at its journal home: http://tcpharm.org Transl Clin Pharmacol is the official journal of the Korean Society for Clinical Pharmacology and Therapeutics. Best regards, Dong-Seok Yim MD, PhD Editor-in-Chief, Translational & Clinical Pharmacology www.tcpharm.org Director, PIPET (Pharmacometrics Institute for Practical Education & Training) Professor Dept. of Pharmacology, College of Medicine The Catholic University of Korea Dept. of Clinical Pharmacology and Therapeutics, Seoul St. Mary's Hospital Office: +82-2-2258-7327 Mobile: +82-10-3065-3845 Fax:: +82-2-2258-7859 email: yi...@catholic.ac.kr