The Pharmacometrics/Modeling and Simulation (M&S) discipline within the Translational and Clinical Pharmacology group at Allergan (Irvine, CA) is seeking a summer intern for 2017. The incumbent will be working under the direction of an M&S scientist on data mining and data visualization with intent to develop a predictive ocular PBPK model to support research and translational science. The incumbent will be interacting closely with ADME scientists and clinical pharmacologists to mine and collect internal and literature ocular PK data. The ideal candidate is preferred to be enrolling in a doctoral or master's program in one of the following disciplines: pharmacokinetics, pharmacometrics, pharmaceutical sciences, biostatistics, data programming or mathematics. Experience in the following areas, though not strictly required, is a plus: PBPK modelling, NONMEM, WinNonlin, SAS and/or R programming. This is an opportunity for the intern to gain exposure to modelling and simulation within a pharmaceutical industry setting.
The employee must conduct their work activities in compliance with all relevant laws, regulations, and regulatory guidelines as well as all Allergan policies and procedures. Main Areas of Responsibilities * Mining Allergan internal, and if necessary, literature ocular PK data in various preclinical species and potentially human * Organize and program datasets to make them amendable for modeling * Perform data visualization for hypothesis testing * Perform data analysis using WinNonlin to calculate various PK parameters in ocular tissues * Create centralized repository folders to store these data * Depending on the incumbent's skillset, develop a predictive PBPK model with the intent to provide recommendations for animal use reduction and cost savings * Present data to group and symposium at the end of the program * In addition, the incumbent is the key contact for Pharmacometrics, and ADME scientists. * The incumbent may attend project team and group meetings to gain industry/project-support experience * In addition, the incumbent is the key contact for Clinical Pharmacologists. Qualifications * B.S. or equivalent degree is required * The ideal candidate is preferred to be enrolled in a doctoral or master's program in one of the following disciplines: pharmacokinetics, pharmacometrics, pharmaceutical sciences, biostatistics, data programming or mathematics. * Must be enrolled as a full-time student at an accredited university and in good academic standing. * Must have valid U.S. work authorization without the need for sponsorship by the company. * Must be able to work full-time for 10-12 weeks for the duration of the internship. * No relocation, transportation, or housing assistance will be provided Contact Kenneth Luu directly or visit this link for more detail and apply: http://agn.referrals.selectminds.com/jobs/intern-non-clinical-translational-sciences-pharmacometrics-clinical-pharmacology-1910 Kenneth T. Luu, PhD Director, Pharmacometrics Non-Clinical and Translational Sciences 2525 Dupont Drive (RD2-2087), Irvine, CA 92612 * 714.246.2803 | 6 714.246.6510 | * ken....@allergan.com This e-mail, including any attachments, is meant only for the intended recipient of the transmission, and may be a confidential or privileged communication. If you received this e-mail in error, any review, use, dissemination, distribution, or copying of this e-mail is strictly prohibited. Please notify us immediately of the error by return e-mail and please delete this message from your system. Thank you in advance for your cooperation.
