Re: [Felvtalk] Knowing the " whys" of Win/Pred/Doxy

[Jennifer Olson]

Alright-  Figaro just pee'd on my bed right- next to me- after I cleaned
box (and then his paws because he made loose poop & got litter ETC on the
bed) caught him in the act. He hasn't been neutered yet. I threw my bedding
into washer, sprayed bed with "Nature's Miracle- No Spray" & resolved I am
NOT remaking bed...
I can hear him crying, like he does when I AM there trying to go to sleep.
Overnight is the biggest lump of time I can be with him so he isn't
COMPLETELY isolated, alone I hate this.
Do I just go to bed now upstairs, or TRY to lay in a dry spot with new
blankets?
='~{

On Mar 1, 2017 4:26 PM,  wrote:

> AMEN TO THAT!  I especially get angry that they do not consider
> alternative medicine a viable tratment.  Unless I get a broken arm, I first
> try alternative meds.  I have not had a flu shot for over 8 years and have
> not had a cold or flu.  I use ginger, turmeric, garlic, onion, cinnamon as
> my anti flu meds.  I just wish we knew more about animals (cats) and herbs,
> which is safe or not safe to use.  Then when something comes up on a
> weekend/holiday and I cannot et my cat to the vet, I would be able to start
> treatment  until I can get to a vet.
>
>  ROBERT CHAPEL  wrote:
> > Amani...
>
> If we consider the extended time frame for Doxy and multiple courses of
> other ABX it makes a certain "intuitive" sense that a non bacterial
> infection is going to require a longer period of time to have whatever
> non-specific ( read... not related to bacterial infection
> necessarily)...  So little research money appears to be devoted to FeLV
> that I don't know that we'll know in the next decade unless the
> continuing demands of consumers ( who do NOT want to hear , in this day
> and age of " Miracles") that there is _ no hope_ for their much loved
> pets) alter this course.I STILL bristle when I think of the closed
> minds in the medical and Veterinary community and SO resent that
> businessmen( Yes...that is what the vast majority are turning into now
> that practices are being forced to consolidate into " Health Systems")..
> hold the power of life and death over us AND our pets.   On the plus
> side with the business model being what it is ( and in contrast to
> the lost art of " professionalism")  The CONSUMER is always right.  Vets
> will be forced, in the future, to work more closely with the "
> customers" wishes as attachment to a given vet will become less common
> as time goes on and people will " practice shop " for the answers they
> want until such time as Vet services become so expensive that insurance
> becomes a " must have " and ultimately go the way of medicine (
> ie...being confined to a slate of approved practitioners...
> againlimiting choice)...  But... there are some years to go before
> that happens and I feel that there IS a window of opportunity happening
> NOW and for the next few  years for people to have some real influence
> on how Vets practice   I am betting, for example, that had I had the
> money to go to a more " well to do " neighborhood where people are more
> demanding and better informed I could have found a vet to cooperate...
> Here in the "sticks" people just blindly accept what the vet has to say
> and they still enjoy the freedom of calling all the shots.   This
> WILL end over the next couple of years.  I learned a lot with this first
> experience and made mistakes that I WILL NOT make again.
>
> BTW  Do you have any literature in support of the AntiRNA effects of
> Doxy... I am SO happy that there are still a couple of things out
> there that we still can get our hands on that don't have to pass muster
> with script pad businessmen  STILL I am also not advocating the the
> medically ill prepared take it upon themselves to decide that THEY will
> decide what is best for their animal... If we are going to go above and
> beyond our Vets advice it would best be with very sound reasoning and an
> EXCELLENT understanding of what we are doing and why.   Anything less
> and the community of Veterinary practitioners could easily dismiss our
> successes as "dumb luck" or ascribe them to " unknown" factors.  I
> think this is particularly important re: Winstrol/Pred/Doxy   I'd hate
> to see people going to their vets asking for this combination of drugs
> and really having an inadequate understanding of why they are asking for
> beyond the fact that it's been recommended on our forum...For
> myself... I am clear on the Whys of Winstrol and Doxy ( though will be
> looking for more lit support on the RNA effects of Doxy) but not clear
> on the whys of the Pred.
> Sorry for taking up so much space here but I'm having an " attack " of
> missing my little guy and am tremulous about being caught in the same
> position if I take in another FeLV as I am inclined to do
>
> >
>
> ___
> Felvtalk mailing list
> 

Re: [Felvtalk] Knowing the " whys" of Win/Pred/Doxy

[Amani Oakley]

Hi Bob

I am unable to attach the literature regarding the ability of Doxycycline to 
interfere with RNA replication and/or interfere with viral infection, but here 
are a few titles to look up on the Internet:

- Antiviral activity of doxycycline against vesicular stomatitis virus in vitro 
- FEMS Microbiol Lett. 2015

- Control of small inhibitory RNA levels and RNA interference by doxycycline 
induced activation of a minimal RNA polymerase III promoter - 2006 Nucleic 
Acids Res. 34

- Inhibitory effect of doxycycline against dengue virus replication in vitro - 
October 2013 Archives of Virology 159(4) 

- Study of the antiviral activity of some derivatives of tetracycline and 
non-steroid anti-inflammatory drugs towards dengue virus - August 2013 Tropical 
Biomedicine 30(4):1-10   (BY THE WAY - DOXYCYCLINE IS A TETRACYCLINE)

- A study of the clinical activity of a gel combining monocaprin and 
doxycycline: a novel treatment for herpes labialis. (2012) J Oral Path Med 
41:61-67



The following paper was interesting in that it explored the role of Doxycycline 
in inhibiting tumour cell proliferation, angiogenesis, metastasis and migration 
of cancerous cells (including leukemic cells) from the bone marrow:

- Doxycycline inhibits leukemic cell migration via inhibition of matrix 
metalloproteinases and phosphorylation of focal adhesion kinase - published 
Molecular Medicine Reports, September 2015 Vol. 12, Issue 3.


Amani

P.S. - By the way, Bob. The other thing that was featured in that show last 
night about the fight against Ebola, is that the same doctor who contracted it 
and was declared symptom-free, later began to develop eye problems and when 
they examined his eye, they found millions of the Ebola viruses in the eye. The 
programme explained that the eye was an area of reduced immunity in the body, 
and thus, the virus had found a breeding ground where it remained, though it 
had been cleared from the rest of the body. They therefore began treating the 
doctor's eye, and the treatment was ultimately successful. It brought to mind 
the problems Yogi had had with his eyes, and I wondered if the answer was 
similar - that the virus had had a toe-hold there.


-Original Message-
From: Felvtalk [mailto:felvtalk-boun...@felineleukemia.org] On Behalf Of ROBERT 
CHAPEL
Sent: March-01-17 5:02 PM
To: felvtalk@felineleukemia.org
Cc: felvtalk@felineleukemia.org
Subject: Re: [Felvtalk] Knowing the " whys" of Win/Pred/Doxy

Amani...

If we consider the extended time frame for Doxy and multiple courses of other 
ABX it makes a certain "intuitive" sense that a non bacterial infection is 
going to require a longer period of time to have whatever non-specific ( 
read... not related to bacterial infection necessarily)...  So little research 
money appears to be devoted to FeLV that I don't know that we'll know in the 
next decade unless the continuing demands of consumers ( who do NOT want to 
hear , in this day and age of " Miracles") that there is _ no hope_ for their 
much loved
pets) alter this course.    I STILL bristle when I think of the closed minds in 
the medical and Veterinary community and SO resent that businessmen( Yes...that 
is what the vast majority are turning into now that practices are being forced 
to consolidate into " Health Systems").. 
hold the power of life and death over us AND our pets.   On the plus side 
with the business model being what it is ( and in contrast to the lost art of " 
professionalism")  The CONSUMER is always right.  Vets will be forced, in the 
future, to work more closely with the " 
customers" wishes as attachment to a given vet will become less common as time 
goes on and people will " practice shop " for the answers they want until such 
time as Vet services become so expensive that insurance becomes a " must have " 
and ultimately go the way of medicine ( ie...being confined to a slate of 
approved practitioners... 
againlimiting choice)...  But... there are some years to go before that 
happens and I feel that there IS a window of opportunity happening NOW and for 
the next few  years for people to have some real influence on how Vets 
practice   I am betting, for example, that had I had the money to go to a 
more " well to do " neighborhood where people are more demanding and better 
informed I could have found a vet to cooperate... Here in the "sticks" people 
just blindly accept what the vet has to say and they still enjoy the freedom of 
calling all the shots.   This WILL end over the next couple of years.  I 
learned a lot with this first experience and made mistakes that I WILL NOT make 
again.

BTW  Do you have any literature in support of the AntiRNA effects of 
Doxy... I am SO happy that there are still a couple of things out there 
that we still can get our hands on that don't have to pass muster with script 
pad bus

Re: [Felvtalk] Knowing the " whys" of Win/Pred/Doxy

[dlgegg]

AMEN TO THAT!  I especially get angry that they do not consider alternative 
medicine a viable tratment.  Unless I get a broken arm, I first try alternative 
meds.  I have not had a flu shot for over 8 years and have not had a cold or 
flu.  I use ginger, turmeric, garlic, onion, cinnamon as my anti flu meds.  I 
just wish we knew more about animals (cats) and herbs, which is safe or not 
safe to use.  Then when something comes up on a weekend/holiday and I cannot et 
my cat to the vet, I would be able to start treatment  until I can get to a vet.

 ROBERT CHAPEL  wrote: 
> Amani...

If we consider the extended time frame for Doxy and multiple courses of 
other ABX it makes a certain "intuitive" sense that a non bacterial 
infection is going to require a longer period of time to have whatever 
non-specific ( read... not related to bacterial infection 
necessarily)...  So little research money appears to be devoted to FeLV 
that I don't know that we'll know in the next decade unless the 
continuing demands of consumers ( who do NOT want to hear , in this day 
and age of " Miracles") that there is _ no hope_ for their much loved 
pets) alter this course.    I STILL bristle when I think of the closed 
minds in the medical and Veterinary community and SO resent that 
businessmen( Yes...that is what the vast majority are turning into now 
that practices are being forced to consolidate into " Health Systems").. 
hold the power of life and death over us AND our pets.   On the plus 
side with the business model being what it is ( and in contrast to 
the lost art of " professionalism")  The CONSUMER is always right.  Vets 
will be forced, in the future, to work more closely with the " 
customers" wishes as attachment to a given vet will become less common 
as time goes on and people will " practice shop " for the answers they 
want until such time as Vet services become so expensive that insurance 
becomes a " must have " and ultimately go the way of medicine ( 
ie...being confined to a slate of approved practitioners... 
againlimiting choice)...  But... there are some years to go before 
that happens and I feel that there IS a window of opportunity happening 
NOW and for the next few  years for people to have some real influence 
on how Vets practice   I am betting, for example, that had I had the 
money to go to a more " well to do " neighborhood where people are more 
demanding and better informed I could have found a vet to cooperate...  
Here in the "sticks" people just blindly accept what the vet has to say 
and they still enjoy the freedom of calling all the shots.   This 
WILL end over the next couple of years.  I learned a lot with this first 
experience and made mistakes that I WILL NOT make again.

BTW  Do you have any literature in support of the AntiRNA effects of 
Doxy... I am SO happy that there are still a couple of things out 
there that we still can get our hands on that don't have to pass muster 
with script pad businessmen  STILL I am also not advocating the the 
medically ill prepared take it upon themselves to decide that THEY will 
decide what is best for their animal... If we are going to go above and 
beyond our Vets advice it would best be with very sound reasoning and an 
EXCELLENT understanding of what we are doing and why.   Anything less 
and the community of Veterinary practitioners could easily dismiss our 
successes as "dumb luck" or ascribe them to " unknown" factors.  I 
think this is particularly important re: Winstrol/Pred/Doxy   I'd hate 
to see people going to their vets asking for this combination of drugs 
and really having an inadequate understanding of why they are asking for 
beyond the fact that it's been recommended on our forum...    For 
myself... I am clear on the Whys of Winstrol and Doxy ( though will be 
looking for more lit support on the RNA effects of Doxy) but not clear 
on the whys of the Pred.
Sorry for taking up so much space here but I'm having an " attack " of 
missing my little guy and am tremulous about being caught in the same 
position if I take in another FeLV as I am inclined to do

>

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Re: [Felvtalk] Knowing the " whys" of Win/Pred/Doxy

[ROBERT CHAPEL]

Amani...

If we consider the extended time frame for Doxy and multiple courses of 
other ABX it makes a certain "intuitive" sense that a non bacterial 
infection is going to require a longer period of time to have whatever 
non-specific ( read... not related to bacterial infection 
necessarily)...  So little research money appears to be devoted to FeLV 
that I don't know that we'll know in the next decade unless the 
continuing demands of consumers ( who do NOT want to hear , in this day 
and age of " Miracles") that there is _ no hope_ for their much loved 
pets) alter this course.    I STILL bristle when I think of the closed 
minds in the medical and Veterinary community and SO resent that 
businessmen( Yes...that is what the vast majority are turning into now 
that practices are being forced to consolidate into " Health Systems").. 
hold the power of life and death over us AND our pets.   On the plus 
side with the business model being what it is ( and in contrast to 
the lost art of " professionalism")  The CONSUMER is always right.  Vets 
will be forced, in the future, to work more closely with the " 
customers" wishes as attachment to a given vet will become less common 
as time goes on and people will " practice shop " for the answers they 
want until such time as Vet services become so expensive that insurance 
becomes a " must have " and ultimately go the way of medicine ( 
ie...being confined to a slate of approved practitioners... 
againlimiting choice)...  But... there are some years to go before 
that happens and I feel that there IS a window of opportunity happening 
NOW and for the next few  years for people to have some real influence 
on how Vets practice   I am betting, for example, that had I had the 
money to go to a more " well to do " neighborhood where people are more 
demanding and better informed I could have found a vet to cooperate...  
Here in the "sticks" people just blindly accept what the vet has to say 
and they still enjoy the freedom of calling all the shots.   This 
WILL end over the next couple of years.  I learned a lot with this first 
experience and made mistakes that I WILL NOT make again.


BTW  Do you have any literature in support of the AntiRNA effects of 
Doxy... I am SO happy that there are still a couple of things out 
there that we still can get our hands on that don't have to pass muster 
with script pad businessmen  STILL I am also not advocating the the 
medically ill prepared take it upon themselves to decide that THEY will 
decide what is best for their animal... If we are going to go above and 
beyond our Vets advice it would best be with very sound reasoning and an 
EXCELLENT understanding of what we are doing and why.   Anything less 
and the community of Veterinary practitioners could easily dismiss our 
successes as "dumb luck" or ascribe them to " unknown" factors.  I 
think this is particularly important re: Winstrol/Pred/Doxy   I'd hate 
to see people going to their vets asking for this combination of drugs 
and really having an inadequate understanding of why they are asking for 
beyond the fact that it's been recommended on our forum...    For 
myself... I am clear on the Whys of Winstrol and Doxy ( though will be 
looking for more lit support on the RNA effects of Doxy) but not clear 
on the whys of the Pred.
Sorry for taking up so much space here but I'm having an " attack " of 
missing my little guy and am tremulous about being caught in the same 
position if I take in another FeLV as I am inclined to do






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Felvtalk@felineleukemia.org
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