during & after megadosing for mostof a year w/ months on end of a liter/day ionic CS never bothered my gut flora that i could tell.  ata a bit of yogurt on cereal pretty regularly & a few helpngs of saurkraut (like on a Reuben) but never supp probiotics.

my understanding today is that while almost all Ag is eliminated through feces it reaches the colon as inactive compounds so impact on flora is slight to none.  i'm sure there're somehow exceptions.
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