Subject: [The vOICe] Mechanisms of cross-modal plasticity in
early-blind subjects
To: [email protected]

Hi All,

For your information. Appended is the abstract of a new publication
this month in the Journal of Neurophysiology.

Best wishes,

Peter Meijer


Seeing with Sound - The vOICe
http://www.seeingwithsound.com/winvoice.htm


Mechanisms of cross-modal plasticity in early-blind subjects.

Abstract.

A variety of studies have demonstrated enhanced blood oxygenation level
dependent responses to auditory and tactile stimuli within occipital cortex as
a result of early blindness. However, little is known about the organizational
principles that drive this cross-modal plasticity. We compared BOLD responses
to a wide variety of auditory and tactile tasks (vs. rest) in early-blind and
sighted subjects. As expected, cross-modal responses were larger in blind than
in sighted subjects in occipital cortex for all tasks (cross-modal plasticity).
Within both blind and sighted subject groups, we found patterns of cross-modal
activity that were remarkably similar across tasks: a large proportion of
cross-modal responses within occipital cortex are neither task nor stimulus
specific. We next examined the mechanisms underlying enhanced BOLD responses
within early-blind subjects. We found that the enhancement of cross-modal
responses due to early blindness was best described as an additive shift,
suggesting that cross-modal plasticity within blind subjects does not originate
from either a scaling or unmasking of cross-modal responsivities found in
sighted subjects.

By Lindsay B. Lewis, Melissa Saenz and Ione Fine.

Source URL:
http://jn.physiology.org/content/104/6/2995

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-- 
shushant bendre physio  therepist from pune camp mobil :9373798593  e
mail id same above or shan .dpt @hotmail.com also skype id
-:dr.shushant  [Vh] thanque  for reeding this mail
 {ammabhagavansharenum}

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