hello can you give me more information about this ? and where is this
research going ? you can send -email on [email protected]
----- Original Message -----
From: "Renuka Warriar" <[email protected]>
To: <[email protected]>
Sent: Sunday, April 10, 2011 7:14 PM
Subject: [AI] Fw: (Keralavision) Scientists make retina from stem cells.
Renuka E,
Section Officer,
ICT Centre for Visually Challlenged,
CHMK Library,
University ofCalicut,
Malappuram Dist.,
Kerala.
----- Original Message -----
From: "Balaram" <[email protected]>
To: <[email protected]>
Sent: Sunday, April 10, 2011 4:22 AM
Subject: (Keralavision) Scientists make retina from stem cells.
By Michelle Roberts Health reporter, BBC News
the growing retina
The growing retina can be seen highlighted green
A part of the eye that is essential for vision has been created in the
laboratory from animal stem cells, offering hope to the blind and
partially sighted.
One day it might be possible to make an eye in a dish, Nature journal
reports.
The Japanese team used mouse stem cells - immature cells that have the
ability to turn into many types of body tissue.
With the right mix of nutrients, the cells changed and began to grow
to make a synthetic retina.
Ultimately, scientists hope they can use this approach to make endless
supplies of retinal cells or indeed whole retinas that can be
transplanted into patients
with visual impairment.
Eventually, it may even be possible to create a whole eye.
A US biotech company has already been granted a license to begin human
trials of a stem cell treatment for blindness.
'Landmark discovery'
The retina is the name given to a diverse group of cells that line the
inside of the back of eye.
Rays of light enter the eye and are focused onto the retina which
produces a picture that is then is sent along the optic nerve for the
brain to interpret.
"Generation of a synthetic retina from embryonic stem cells is a
landmark discovery that will help enormously our understanding of
blinding eye disease"
Professor James Bainbridge of Moorfields Eye Hospital NHS Foundation
Trust
The eye and the brain together produce the images that we see.
Retinal diseases can cause severe vision loss or blindness if left
untreated.
Retinitis pigmentosa and age-related macular degeneration (AMD) are
the most common causes of blindness in old age, and involve the
gradual and normally
irreversible destruction of retinal cells.
In the Japanese study, the cultured stem cells spontaneously organised
themselves into a complex structure that resembled the developing
embryonic eye.
The three-dimensional, layered structure was reminiscent of the optic
cup, a two-walled pouch-like structure, which ultimately develops into
the inner and
outer layers of the retina.
The scientists said they were surprised at how well the cells
organised themselves with little intervention from them.
They said: "Self-formation of fully stratified 3D neural retina
tissues heralds the next generation of generative medicine in retinal
degeneration therapeutics,
and opens up new avenues for the transplantation of artificial retinal
tissue sheets, rather than simple cell grafting."
Professor James Bainbridge of Moorfields Eye Hospital NHS Foundation
Trust said: "Generation of a synthetic retina from embryonic stem
cells is a landmark
discovery that will help enormously our understanding of blinding eye
disease.
"It is particularly exciting that this could also provide a source of
cells for transplantation."
Barbara McLaughlan of the RNIB charity said: "This piece of research
contributes to the ongoing efforts to harness stem cell research to
benefit patients
with a number of eye diseases.
"We welcome these efforts particularly where they move from early
laboratory research in mice to trials in humans that are an essential
part of developing
safe and effective treatments..
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