Friends,

I have two adult graduate sons 31/26 years suffering from RP currently in
Mumbai both lost job due to poor vision, this is to share information.
Elder one with MBA  taking training in NAB Mumbai.

*Surgeons in Manchester have performed the first bionic eye implant in a
patient with the most common cause of sight loss in the developed world.*

Ray Flynn, 80, has dry age-related macular degeneration which has led to
the total loss of his central vision.

He is using a retinal implant which converts video images from a miniature
video camera worn on his glasses.

He can now make out the direction of white lines on a computer screen using
the retinal implant.

Mr Flynn said he was "delighted" with the implant and hoped in time it
would improve his vision sufficiently to help him with day-to-day tasks
like gardening and shopping.

*Weed or flower?*

The Argus II implant, manufactured by the US firm Second Sight, has
previously been used to restore some vision to patients who are blind as a
result of a rare condition known as retinitis pigmentosa.

The operation, at Manchester Royal Eye Hospital, is the first time it has
been implanted in a patient with age-related macular degeneration (AMD)
which affects at least half a million people in the UK to some extent.

I met Ray Flynn last month, on the morning of his surgery and he explained
that although his retained his peripheral vision, his central sight had
disappeared.

He said: "I'm unable to put the numbers in for my card when paying in a
shop or at the bank, and although I was a keen gardener, I can't tell the
weeds from the flowers anymore."

Ray Flynn's central vision has been lost due to age-related macular
degeneration

Mr Flynn said he had to sit very close to the television to see anything.

He had given up going to see Manchester United play football as he cannot
make out what is happening.

The operation took four hours and was led by Paulo Stanga, consultant
ophthalmologist and vitreo-retinal surgeon at Manchester Royal Eye Hospital
and professor of ophthalmology and retinal regeneration at the University
of Manchester.

He said: "Mr Flynn's progress is truly remarkable, he is seeing the outline
of people and objects very effectively.

"I think this could be the beginning of a new era for patients with sight
loss."

*How it works*

The bionic eye implant receives its visual information from a miniature
camera mounted on glasses worn by the patient.

The images are converted into electrical pulses and transmitted wirelessly
to an array of electrodes attached to the retina.

The electrodes stimulate the remaining retina's remaining cells which send
the information to the brain.

In a test, two weeks after surgery, Mr Flynn was able to detect the pattern
of horizontal, vertical and diagonal lines on a computer screen using the
implant.

He kept his eyes closed during the test so that the medical team could be
sure that the visual information was coming via the camera on his glasses
and the implant.

Mr Flynn said: "It was wonderful to be able to see the bars on the screen
with my eyes closed."

The implant cannot provide any highly detailed vision - but previous
studies have shown it can help patients to detect distinct patterns such as
door frames and shapes.

Prof Stanga said that in time, Mr Flynn should learn how to interpret the
images from the implant more effectively.

*Dry AMD*

·         There are two forms of age-related macular degeneration - dry and
wet.

·         The dry form affects 85% of AMD patients and causes gradual loss
of central vision, but does not affect peripheral vision.

·         The Macular Society estimates that 44,000 people a year in the UK
develop dry AMD.

Four more patients with dry AMD will receive the implant at Manchester
Royal Eye Hospital, as part of a clinical trial.

Prof Stanga said: "We hope these patients will develop some central visual
function which they can work in alongside and complement their peripheral
vision."

We are very excited by this trial and hope that this technology might help
people, including children with other forms of sight loss."

The Argus II costs about £150,000, including treatment costs, although all
the patients on the trial will be treated free of charge.

Gregoire Cosendai of Second Sight Medical Products, described the AMD study
as "totally groundbreaking research".

The trial is being held in the Manchester Clinical Research Facility -
funded by the National Institute for Health Research and Wellcome Trust,
which aims to bring new drugs and medical devices to patients.

Cathy Yelf, of the Macular Society, said: "This is an exciting result and
we are following the progress of these trials with great interest.

"Macular degeneration can be a devastating condition and very many people
are now affected as we live longer.

"These are early trials but in time this research may lead to a really
useful device for people who lose their central vision."


Best Regards,
Jyotindra Ganatra
Cell # +971 56 1773940


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