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Scientists find clue to cause of possible carcinogen in french fries, 
other foods 
Sun Sep 29, 2:59 PM ET
By LAURAN NEERGAARD, AP Medical Writer 

WASHINGTON - Scientists have found a clue to the chemical reaction that 
may cause potato chips, french fries and other fried or baked starchy 
foods to build up high levels of a possible cancer-causing substance. 

  

The suspect is asparagine, a naturally occurring amino acid that, when 
heated with certain sugars such as glucose, leads to the formation of 
the worrisome substance acrylamide. 

The U.S. Food and Drug Administration ( news - web sites) has made 
studying acrylamide's risk and determining how to lower its levels in 
food one of its highest research priorities, according to a plan that 
agency officials were to discuss Monday with consumer groups and food 
manufacturers. 

Canada's government made the discovery about the suspect chemical 
reaction and has ordered food manufacturers to look for ways to alter it 
and thus lower levels of acrylamide in food. Cincinnati-based 
manufacturer Procter & Gamble Co. says its scientists, too, have found 
the asparagine connection. 

It is the first clue to emerge in the mystery of acrylamide since 
Swedish scientists made the surprise announcement in the spring that 
high levels of the possible carcinogen are in numerous everyday foods: 
french fries, potato chips, some types of breakfast cereals and breads � 
plenty of high-carbohydrate foods that are fried or baked at high 
temperatures. The chemical was not found in boiled foods, which are 
cooked at lower temperatures. 

Sweden's findings were confirmed in June by governments in Norway, 
Britain and Switzerland, and preliminary testing of several hundred 
foods by the FDA suggests U.S. foods contain similar acrylamide levels, 
said Richard Canady, who is directing the agency's assessment of 
acrylamide's risk. 

Acrylamide is used to produce plastics and dyes and to purify drinking 
water. Although traces have been found in water, no one expected high 
levels to be in basic foods. 

It causes cancer in test animals, but it has not been proved to do so in 
people. Still, Swedish scientists have said the levels are high enough 
that foodborne acrylamide might be responsible for several hundred cases 
of cancer in that country each year. 

In the United States, the FDA has been careful to caution that 
acrylamide so far is only a suspected carcinogen. The FDA has not yet 
advised consumers to alter their diets to avoid it. 

Still uncertain is whether the FDA, once it finishes testing different 
foods next year, will publicly identify which brands contain the most 
acrylamide � information wanted by consumer advocates. 

For now, Canady said, "We want to reinforce ... eating a balanced diet 
with plenty of fruits and vegetables. That's the best way to ensure that 
you're getting adequate nutrition." 

The food industry stresses that while fried potato products are getting 
most of the bad publicity � most testing so far shows the highest levels 
in them � acrylamide is in a wide variety of foods. Procter & Gamble 
said Friday that its testing found acrylamide in such previously 
unimplicated foods as roasted asparagus and banana chips. 

___ 

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