Hi.

On Fri, Nov 4, 2011 at 10:15 PM, Peter Kang <h.peter.k...@gmail.com> wrote:
> Hello,
>
> I have a question about the CRLMM algorithm implemented in Aroma. Is
> this the CRLMM v2 algorithm?

Yes.  It is implemented by porting parts of oligo as well as utilizing
existing methods in the 'oligo' package.

> It seems the v2 algorithm is no longer
> available in the oligo package.

I'm not aware of the status and plans of oligo/crlmm (check with their
maintainers), but at least I've just checked that in oligo v1.18.0 you
can still access the justCRLMMv2() function as:

oligo:::justCRLMMv2

and it still works, cf. the following aroma.affymetrix test:

pathname <- 
"testScripts/replication/chipTypes/Mapping50K_Hind240,Xba240/test20081208,oligo,CRLMM.R";
pathname <- system.file(pathname, package="aroma.affymetrix");

which is basically doing what is in the 'CRLMM genotyping (100K and
500K)' vignette:

http://aroma-project.org/vignettes/CRLMM100K500K

Hope this helps

Henrik

> It is implemented in the crlmm
> package, but this is specific to Affy 5.0 and 6.0 arrays and Illumina,
> and the data that I have is from Affy 500k arrays. Basically I am
> looking for a CRLMM v2 algorithm implementation for Affy 500k arrays.
>
> Thanks!
>
> --
> When reporting problems on aroma.affymetrix, make sure 1) to run the latest 
> version of the package, 2) to report the output of sessionInfo() and 
> traceback(), and 3) to post a complete code example.
>
>
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-- 
When reporting problems on aroma.affymetrix, make sure 1) to run the latest 
version of the package, 2) to report the output of sessionInfo() and 
traceback(), and 3) to post a complete code example.


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