Hi there,

I'm new to processing Affy SNP6 chips and so am mainly experimenting with 
different methods to date. I ran CRMAv2 and followed steps 1-4 from the 
vignette (http://aroma-project.org/vignettes/CRMAv2). For step 5, I want to 
do a paired analysis.

Previously I've used DNAcopy to perform CBS for other array types, and 
would like to follow a similar procedure, which includes smoothing prior to 
segmentation. Is this possible using the aroma.affymetrix package? So far 
I've followed the vignette for paired CNA analysis (
http://aroma-project.org/vignettes/pairedTotalCopyNumberAnalysis) but 
haven't seen any options for smoothing. 

thank you very much,

emilie

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