Dear all,

I'm working on a GWAS dataset generated with the Affymetrix V2 SNP chips in 
the dog (http://www.broadinstitute.org/mammals/dog/caninearrayfaq.html).
I'm using the aroma.package as other packages seem to not support this 
chip. 

I've followed the manual and everything seemed to work fine, until I tried 
to do the "CrlmmModel" function, then I get the following error:

[2014-05-22 17:23:17] Exception: Cannot fit CRLMM model: Unsupported/unsafe 
chip type: DogSty06m520431P

  at #01. CrlmmModel(ces, tags = "*,oligo")
          - CrlmmModel() is in environment 'aroma.affymetrix'
Error: Cannot fit CRLMM model: Unsupported/unsafe chip type: DogSty06m520431P


All the previous steps seemed to work fine, so I'm a bit surprised by this 
error. The code so far was: 

cdf <- AffymetrixCdfFile$byChipType("DogSty06m520431P")
cdf
csR <- AffymetrixCelSet$byName("OCD", cdf=cdf)
csR
ces <-justSNPRMA(csR, normalizeToHapmap=FALSE, returnESet=FALSE, verbose=TRUE)
ces
crlmm <- CrlmmModel(ces,tags="*,oligo")


Can anyone help me to resolve this issue? In addition: I planned to work 
further with this dataset in GenABEL. Can I directly use the output from 
extractGenotypes as input for GenABEL?


Thank you!


Best regards,

Bart Broeckx

DVM, PhD Student

Laboratory for Pharmaceutical Biotechnology

Ghent University


Output from sessionInfo()

> sessionInfo()R version 3.0.3 (2014-03-06)
Platform: x86_64-w64-mingw32/x64 (64-bit)

locale:
[1] LC_COLLATE=Dutch_Belgium.1252 
[2] LC_CTYPE=Dutch_Belgium.1252   
[3] LC_MONETARY=Dutch_Belgium.1252
[4] LC_NUMERIC=C                  
[5] LC_TIME=Dutch_Belgium.1252    

attached base packages:
[1] parallel  stats     graphics  grDevices utils    
[6] datasets  methods   base     

other attached packages:
 [1] Biostrings_2.30.1       XVector_0.2.0          
 [3] Biobase_2.22.0          oligoClasses_1.24.0    
 [5] BiocGenerics_0.8.0      BiocInstaller_1.12.1   
 [7] aroma.light_1.32.0      matrixStats_0.8.14     
 [9] aroma.affymetrix_2.12.0 aroma.core_2.12.1      
[11] R.devices_2.9.2         R.filesets_2.4.0       
[13] R.utils_1.32.4          R.oo_1.18.0            
[15] oligo_1.26.6            IRanges_1.20.7         
[17] affxparser_1.34.2       R.methodsS3_1.6.1      

loaded via a namespace (and not attached):
 [1] affyio_1.30.0         aroma.apd_0.5.0      
 [3] base64enc_0.1-1       bit_1.1-12           
 [5] codetools_0.2-8       DBI_0.2-7            
 [7] digest_0.6.4          DNAcopy_1.36.0       
 [9] ff_2.2-13             foreach_1.4.2        
[11] GenomicRanges_1.14.4  iterators_1.0.7      
[13] preprocessCore_1.24.0 PSCBS_0.41.4         
[15] R.cache_0.9.2         R.huge_0.8.0         
[17] R.rsp_0.15.0          splines_3.0.3        
[19] stats4_3.0.3          tools_3.0.3          
[21] zlibbioc_1.8.0       > traceback()No traceback available 


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traceback(), and 3) to post a complete code example.


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