Hi Chengyu,

On 4 February 2015 at 15:45, Chengyu Liu <chengyu.liu...@gmail.com> wrote:

> Thanks Sam for sharing the information.
> But I dont understand, why there are chromosome 24 and 25 (autosomal
> chromosome 1-22, X(23), Y(24))?
>

yes, 23 is chromosome X and 24 is chromosome Y. Chromosome 25 is for
pseudo-autosomal regions in X.


Are you using any other package than aroma.affymetrix ?
>

Yes, I am using ChAS to find CNAs.


> Are you interested in total copy number or allele-specific copy number
> analysis ?
>

I am interested in allele-specific copy number analysis.

>
> Now I am working on allele-specific copy number analysis. But I am stuck
> in the steps where copy number alterations are called and LOHs are
> identified.  Do you have any suggestions?
>

ChAS actually does lot analysis along with calling CNV. LOH is one of them.
Probably it is better if you can use that.


> How about you ?
>

We are not yet concerned about LOH till now. Maybe in future.

>
> Br,
> C.Y
>
> On Wednesday, February 4, 2015 at 10:37:46 AM UTC+2, Sam Padmanabhuni
> wrote:
>>
>> HI Chengyu,
>>
>> Yes, I do have chromosome 23, 24 and 25. We are only interested in CNAs
>> in autosomal chromosomes so not going to include X and Y chromosomes in
>> further analysis.
>>
>> Best,
>> Sam.
>>
>>
>> On 4 February 2015 at 10:31, Chengyu Liu <chengyu...@gmail.com> wrote:
>>
>>> Hi Sam,
>>>
>>> I would like to discuss something about cytoscanHD array. Did you find
>>> that when you have done preprocessing, there are chromosome 24 and 25 ?
>>>
>>> Br,
>>> Chengyu
>>>
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Best,
Sam.

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