Dear
all,
We are writing to let you know of a new
webserver http://www.webact.org that has
been developed for the generation, and online display of ACT comparison files .
We have made available pre-computed up to date
comparisons of publicly available annotated microbial
genomes.
The results of the
pre-computed blast comparisons are stored in a relational database along with
the full embl format records for each of the genome sequences.
Storing the
data thus allows the records to be retrieved in a number of ways,
including specifying a gene of interest in one genome for display of the
corresponding regions of similarity (if present) in another genome. Comparisons are then presented for display
through an applet version of ACT or are available compressed for
download.
Furthermore,
WebACT allows users to cut and paste sequences (raw or annotated), upload
their own sequence files (raw or annotated) or query public databases based on
accession numbers / EMBL IDs. Comparisons are generated
(BlastN or TBlastX - options can be changed) and presented for viewing
online through the applet version of
ACT.
All genome
comparisons, generated
comparisons and sequences are made available compressed for
downloading and viewing using the standalone version of ACT.
WebACT is fully
documentated and we are releasing the facility to the ACT mailing list
in BETA version, the final version will include a wider number
of genomes (including viruses and archaebacteria) and is being based
on EBI's Genome Reviews.
The WebACT applet
requires that JAVA2 be installed on the users machine, details of which can be
found on the Software Requirements page.
We would very much appreciate any feedback,
comments and suggestions you may have.
best
regards
David
Aanensen ([EMAIL PROTECTED])
and James Abbott ([EMAIL PROTECTED])
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