> 1- We have around 100K users and 380 hosted email domains, 
> is one ASSP server enough to handle the load for these 
> accounts to both filter SPAM and Virus infected emails ?. 
> A suggestion for server specs would be great !

I'd better be using a couple of ASSP 2.0 sharing a common 
backend database and configured as primary and secondary 
MX in DNS and as smarthost for outbound email; in this latter
case the backend mailserver should point to an hostname
which will resolve with both ASSP boxes IP so that you'll
have some kind of "round robin" for outbound email


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