If you are really sold on a fancy UI and wish to consider the other poster's 
"download the
whole database idea" and allow automated access without lots of repeated code 
versions,
java is the obvious choice for everything. An applet for the browser is easily 
invoked standalone
with little additional effort. Java is fast enough for most UI's and has the 
flexibility for a programming
language with lots of built in UI support. 

This may sound a bit silly but I also wouldn't dismiss support for mobile 
phones. I used to find myself
surfing pubmed or otherwise looking into stuff while on the freeway or waiting 
in various locations. 
If you have something which is well treated with a GUI that looks like a video 
game, maybe it would
be a natural spare time activity on mobile devices :)



Mike Marchywka
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> Date: Wed, 9 Apr 2008 23:11:34 +0530
> From: [EMAIL PROTECTED]
> To: [email protected]
> Subject: Re: [BiO BB] Advanced web query interfaces for biological databases
>
> It will be an interesting UI design.
> Now many bioinformatics web resources are coming up with intuitive use of js
> libraries like YUI, scriptaculous etc. Flex is also an excellent tool for
> revolutionary UI development. If I were you, I would have used a combination
> of js library + flex
>
> thats my 2 cents
> cheers,
> Shameer
>
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