Thats a bit of an ill-posed question. Most commonly seen among all  
genes? Among all solved protein structures? Superfamilies with the  
largest number of family members? Most frequent if you would take a  
random sample of proteins from a living cell? ... There are many  
possible sets to choose from, not all of them in some way  
biologically relevant.

If you want an overview of what's out there, browse CATH or SCOP.  
CATH architectures and SCOP superfamilies probably come closest to a  
concept of "representative".

http://www.cathdb.info/
http://scop.mrc-lmb.cam.ac.uk/scop/


HTH,
Boris


On 30-Jun-08, at 11:07 PM, mahesh chandran wrote:

> Hi friends ,just help  me out with this  problem.How to find the  
> highly
> representative  protein folds ?In other words, i would like to know  
> the top
> 10 folds that are most  commonly seen in proteins.
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