2008/12/23 Ashwathy <[email protected]>: > dear friends, > please help me to find answer to some queries.... > > Is there any difference between Protein Interaction Network (PIN) and > Protein-Protein Interaction Network (PPIN) ? > If so please help me to find what the difference is..
No, its just two different names for the same idea. > and also, > is there any advantages other than finding the connectivity of the protein, > by investigating the PIN? I mean whether it is possible to explore the > attributes (both structural and functional) of a protein through it's PIN? Yes, there are lots of ideas. For example, some people say that highly connected proteins are more likely to be essential, or evolve slower. The 'guilt by association' method is a way to infer protein function or structure from the known function or structure of its interacting partners. There are lots of papers (sorry I didn't reference any here). Dan. > Aswathi > Centre for Bioinformatics > Kerala University > _______________________________________________ > BBB mailing list > [email protected] > http://www.bioinformatics.org/mailman/listinfo/bbb > _______________________________________________ BBB mailing list [email protected] http://www.bioinformatics.org/mailman/listinfo/bbb
