Browsing, searching, analyzing and visualizing pathway data are easier with the 
new and updated Reactome.

Reactome has released a new web interface for its open-source curated database 
of pathways and reactions.

New features include:


 *   A newly designed website with an intuitive user interface for exploring 
pathway knowledge and a new suite of data analysis tools


 *   Pathway Browser, an SBGN-based visualization system of pathway diagrams 
with advanced navigation features, including zooming, scrolling and event 
highlighting.


 *   PSIQUIC web services to overlay our curated pathway diagrams with 
molecular interaction data from the Reactome Functional Interaction Network and 
external interaction databases such as IntAct, BioGRID, ChEMBL, iRefIndex, 
MINT, and STRING.


 *   Pathway and Expression Analysis tools, which allow researchers to analyze 
experimental datasets by providing ID mapping, pathway assignment and 
over-representation analysis.


 *   Reactome Functional Interaction Network Cytoscape plugin that is useful in 
the discovery of network patterns related to cancer and other types of disease.


 *   Improved tools for display and analysis of Ensembl Compara ortholog-based 
pathway predictions in 20 non-human species, including the 12 species of the GO 
Reference Genome Annotation project.


 *   A species Comparison tool, which allow users to compare pathways from 
another species with human data by providing an overlap indicating the degree 
of orthology between the two species.

A full description of the new features offered by Reactome is available on the 
new Reactome website at http://www.reactome.org.

Reactome is a collaboration between groups at the Ontario Institute for Cancer 
Research, Cold Spring Harbor Laboratory, New York University Medical Center, 
and The European Bioinformatics Institute.  Freely available to academic, 
clinical, and commercial researchers and scientists worldwide, the Reactome 
database offers pathway data encapsulating areas of human biology ranging from 
basic pathways of metabolism to complex events such as GPCR signaling and 
apoptosis, extracted from the published literature by Reactome curatorial staff 
and cross-referenced to a wide range of standard biological databases. Reactome 
data and software are distributed under the terms of the Creative Commons 
Attribution 3.0 Unported License.

For more information contact:
Robin Haw
Email: [email protected]<mailto:[email protected]>
Tel: 647-260-7985


Robin Haw, PhD
Scientific Associate
Manager of Reactome Outreach

Ontario Institute for Cancer Research
MaRS Centre, South Tower
101 College Street, Suite 800
Toronto, Ontario, Canada M5G 0A3

Tel:         647-260-7985
Toll-free: 1-866-678-6427
http://www.oicr.on.ca<http://www.oicr.on.ca/>
http://www.reactome.org<http://www.reactome.org/>

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