Cambridge Healthtech Institute & Bio-IT World Announce Upcoming Short Course:
Identification of Druggable Sites for Protein-Protein Interaction Targets June 8, 2011 (6:00 - 9:00 p.m.) Royal Sonesta Hotel Boston, Cambridge, MA Register at https://chidb.com/register/2011/sbd/reg.asp On June 8, 2011, a dinner short course (6:00 - 9:00 p.m.) will take place at the conclusion of day one of CHI's Eleventh Annual Structure-Based Drug Design conference. Delegates attending CHI's Structure-Based Drug Design conference are invited to attend, as well as others from the local area. About the course: Despite the growing number of examples of small molecule inhibitors that disrupt protein-protein interactions (PPIs), the origin of druggability is poorly understood. This course is designed to demonstrate the use of computational methods to determine the most likely structure of the complex formed by interacting proteins, identify potentially druggable sites in the interface, determine whether the target is druggable, and provide information on potential ligands. Participants will study a number of targets using web-based software (including PIPER and ClusPro, currently the best protein docking tools available) on their laptops. A light dinner will be served. Course Instructors: Sandor Vajda, Ph.D., Professor, Departments of Biomedical Engineering and Chemistry, Boston University Dima Kozakov, Ph.D., Research Assistant Professor, Departments of Biomedical Engineering, Boston University The problem of disrupting protein-protein interactions Predicting the structure of protein-protein complexes using fragment-based identification of binding hot spots Druggability of binding sites determined by the hot spots Identification of functional groups with preferential binding to hot spots Comparison of computational and experimental approaches. Additional information and registration details for this course and conference is available at http://www.healthtech.com/sbd or call CHI at 781-972-5400. A separate registration is required to attend the Structure-Based Drug Design conference that is scheduled for June 6-8, 2011. If you would like to also attend the Structure-Based Drug Design conference, you can save up to $350 if you register by Friday, March 11. Contact: James Prudhomme Cambridge Healthtech Institute 250 First Avenue, Suite 300 Needham, MA 02494 Phone: 781-972-5400 Fax: 781-972-5425 www.healthtech.com _______________________________________________ BBB mailing list [email protected] http://www.bioinformatics.org/mailman/listinfo/bbb
