Hi, I'm a newbie to the field of bioinformatics and I'm trying to learn about micro-arrays (e.g affymetrix genechip ) and about pre-processing algorithms. I understand that one of the most widely used algorithms for pre-processing is the RMA algorithm. This algorithm is the algorithm I'm trying to understand. It's supposed to have 3 steps ( background correction, normalization, summarization ). My question is what are the inputs and the outputs of such a pre-processing algorithm. Is the "input" data for a pre-processing algorithm a CEL file ?? Is this CEL file the file that the micro-array computer scanner returns as a result to the user ??? Is the CEL an image file viewable in an image viewer and if so where can I find sample CEL files ? And what is the output of the algorithm ?
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