"Nathalie Conte" <nco...@ebi.ac.uk> wrote in message 
news:9d0654e0-8ec0-4051-87ca-541f90931...@ebi.ac.uk...
Dear all, 

Thanks a lot for the codes various people which all work perfectly!! I have 
also discover some useful functions (eval and state) which can also be very 
helpful for this kind of data.

In the light of this, my dataset got more complicated, now there are 3 layers 
of hashes and I need now to calculate across those hashes for each name, 
I have tried to apply some of the code structure which were kindly provided and 
worked well for my first question, although as the data structure is now more 
complicated and I need to assess the data accross hashes makes it more complex 
and I din’t manage to get  a solution for this. Again, any help would be 
greatly appreciated. 
##############
this is the dataset  now
$VAR1 = {
          '100 ' => {
                      'y' => {
                               '1' => 88,
                               '3' => 89,
                               '5' => 99
                             },
                      'x' => {
                               '1' => 97,
                               '3' => 117,
                               '5' => 107
                             },
                      'z' => {
                               '1' => 95,
                               '3' => 97,
                               '5' => 94
                             }
                    },
          '101 ' => {
                      'y' => {
                               '1' => 188,
                               '3' => 189,
                               '5' => 199
                             },
                      'x' => {
                               '1' => 197,
                               '3' => 1117,
                               '5' => 1107
                             },
                      'z' => {
                               '1' => 195,
                               '3' => 197,
                               '5' => 194
                             }
                    }
        };

########################
For each $name (100 and 101)- there are 3 levels, x, y and z -Times are 1,3,5 
for all datasets, across x, y and z .
What needs to be calculated now with this more complex structure,  is  for each 
name, a calculation across the 3 hashes, for the 3 times.

for 100:
first line : no action
second line : should reflect the difference between time 3 and time 1 across 
x,y and z (x3-x1)+(y3-y1)+(z3-z1)
time :3 - 1 =2, 
value: calculation:  x (value 3(117)-value 1(97) + y (value 3 (89)) - value 1 
(88)) + z (value 3 (97) - value 1 (95))
total should be : 117-97 + 89-88 +97-95 =13 
third line: should reflect difference between time 5 and time 3 AND time 5 and 
time 1
time : 5-3, and 5-1
value: calculation: difference between time 5 and time 3 : x (-value5 (107) - 
value 3(117)) + y (value5 (99)- value 3 (89)) + z (value 5 (94) - value 3 (97) 
) = -3 total
      difference between time 5 and time 1 : x (-value5 (107) - value 1(97)) + 
y (value5 (99)- value 1 (88)) + z (value 5 (94) - value 1 (95) ) = 20 total

#######################
my partial code,
#!/usr/local/bin/perl
use strict;
use warnings;
use feature 'state';

use Data::Dumper qw(Dumper);
my %hall;

$hall{"100 "}{'x'}{1}   = 97;
$hall{"100 "}{'x'}{3}    = 117;
$hall{"100 "}{'x'}{5}    = 107;
$hall{"100 "}{'y'}{1}   = 88;
$hall{"100 "}{'y'}{3}  = 89;
$hall{"100 "}{'y'}{5}  = 99;
$hall{"100 "}{'z'}{1}  = 95;
$hall{"100 "}{'z'}{3}  = 97;
$hall{"100 "}{'z'}{5}  = 94;
$hall{"101 "}{'x'}{1}   = 197;
$hall{"101 "}{'x'}{3}    = 1117;
$hall{"101 "}{'x'}{5}    = 1107;
$hall{"101 "}{'y'}{1}   = 188;
$hall{"101 "}{'y'}{3}  = 189;
$hall{"101 "}{'y'}{5}  = 199;
$hall{"101 "}{'z'}{1}  = 195;
$hall{"101 "}{'z'}{3}  = 197;
$hall{"101 "}{'z'}{5}  = 194;

print Dumper \%hall;
print "----------------\n";

foreach  my $name ( sort keys %hall) {
print "name.$name\n";
    foreach  my $subject (sort keys %{ $hall{$name} }) {
print "suject.$subject\n";

   foreach  my $values  ( sort  keys %{ $hall{$name}{$subject}}) {
        state ($lgrade,$lsubject,$lname,$ltimes);

       my $grade = $hall{$name}{$subject}; 
print "grade is .$grade\n"; # this is not working and gives a reference!
my $times = $hall{$name}{$subject}{$values};
print "time is .$times\n";
      
        if (eval { $lgrade and $lname eq $name }) { 

            my ( $grade_diff, $times_diff) = ( $grade - $lgrade, 
$times-$ltimes);
            print "$name,  
$grade-$lgrade=$grade_diff:$name,$times-$ltimes=$times_diff \n";
        }




        ($ltimes, $lgrade,$lname) = ($times, $grade,$name);
    }
}
}

many thanks again for any tips/help,

I see Jim Gibson has solved this but I thought I’d add another solution.

Although it is a little more complex, it is shorter than Jim’s. It makes use of 
2 modules: List::Util=(sum) and List::MoreUtils=(uniq).

#!/usr/bin/perl
use strict;
use warnings;
use List::Util 'sum';
use List::MoreUtils 'uniq';

my %hall = (
          '100 ' => {
                      'y' => {
                               '1' => 88,
                               '3' => 89,
                               '5' => 99
                             },
                      'x' => {
                               '1' => 97,
                               '3' => 117,
                               '5' => 107
                             },
                      'z' => {
                               '1' => 95,
                               '3' => 97,
                               '5' => 94
                             }
                    },
          '101 ' => {
                      'y' => {
                               '1' => 188,
                               '3' => 189,
                               '5' => 199
                             },
                      'x' => {
                               '1' => 197,
                               '3' => 1117,
                               '5' => 1107
                             },
                      'z' => {
                               '1' => 195,
                               '3' => 197,
                               '5' => 194
                             }
                    }
);

for my $name (sort keys %hall) {
    my $href = $hall{$name};
    my @keys = uniq sort {$a <=> $b} map keys %$_, values %$href;
    
    for my $i (0 .. $#keys) {
        for my $j ($i+1 .. $#keys) {
            my $sum = sum( map $_->{$keys[$j]}, values %$href) - 
                               sum( map $_->{$keys[$i]}, values %$href);
            printf "%s $keys[$j] minus $keys[$i] %s\n", $name, $sum;
        }
    }
}

It gave as output:

100  3 minus 1 23
100  5 minus 1 20
100  5 minus 3 -3
101  3 minus 1 923
101  5 minus 1 920
101  5 minus 3 –3

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