http://madison.indymedia.org/newswire/display_any/19488

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"Our lives begin to end the day we become silent about things that matter."
- Martin Luther King, Jr. 

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Fetal Sensitivity to Pollutants From Vehicles, Power Plants and Other Combustion 
Sources
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Wednesday, 20 October 2004
by Michael T. Neuman
Email: [EMAIL PROTECTED]


Summary: A recent study by New York's Columbia Center for Children's Environmental 
Health concludes that babies in the womb are more sensitive than their mothers to 
pollutants from motor vehicle tailpipes, power plant smokestacks, second-hand smoke 
and other combustion sources, underscoring the importance of reducing those pollution 
sources in the environment.

Published in the scientific journal "Environmental Health Perspectives" (V. 110, 10), 
the study examined the effect of prenatal exposure to combustion residual pollutants 
called "polycyclic aromatic hydrocarbons" (PAHs). 

PAHs, such as benzo[a]pyrene (BaP), are widespread air contaminants released by 
transportation vehicles, power generation, and other combustion sources. The study 
found that, despite the protection provided the fetus by the placenta during fetal 
development, DNA damage in newborns (from PAHs) was still as high as the level of DNA 
damage in the mothers. 

"These results raise serious concern", said lead study author Dr. Frederica Perera. 
"What gets across the placenta is not detoxified, and the damage to the DNA is not 
repaired in the fetus as it is in the mother," she said. 

The DNA damage from increased exposure to PAHs increases the likelihood that babies 
will experience developmental problems and increased cancer risk, said Dr. Perera. 
Other studies have demonstrated that the placenta normally reduces the fetal dose of 
PAHs to an estimated one-tenth of the dose of the mother. However in this study, the 
research team found an equal amount of PAH-induced DNR damage in the mothers and the 
newborns. This led them to believe that the fetus is 10 times more vulnerable as 
adults are to the carcinogenic effects of the same pollutants. 

The study involved 265 pairs of mothers and newborns in New York City and was 
conducted by New York's Columbia Center for Children's Environmental Health Center. 
The mothers were non-smoking African American or Latina women living in New York's 
Washington Heights, Central Harlem and South Bronx districts. 

Researchers examined blood samples from the mothers and from the umbilical cords of 
the newborns for two key biomarkers: carcinogen-DNA adducts (associated with increased 
cancer risk), and cotinine (a measure of tobacco smoke exposure – in this case, 
secondhand tobacco smoke, since the mothers were all nonsmokers). 

Dr. Perera, who also serves as the Director of the Children's Environmental Health 
Center, said the study underscores the importance of reducing levels of air pollution 
in cities.

This study comes on the heels of numerous other health studies showing links between 
increased fuel burning in motorized vehicles, power plants and other fossil fuel 
combustion sources, and increased risk of serious health effects. Other studies show 
links between fossil fuel burning in motor vehicles, airplanes and coal-fired power 
plants, and increasing incidences of asthma and cancer, as well as increased 
occurrances of heart attack and stroke in populations residing in close proximity to 
such combustion sources.

The full name of the study is:
"Biomarkers in maternal and Newborn Blood Indicate Heightened Fetal Susceptibility to 
Procarcinogenic DNR Damage"
http://www.ccceh.org/news-events/CCCEH%20PRESS%20RELEASE%20(Jun23).htm

See also:

HIGHWAY HEALTH HAZARDS:
http://www.sierraclub.org/hhh/HHHFinalReport6-28-04.pdf

IMPACTS OF CO2 AND CLIMATE CHANGE
ON PUBLIC HEALTH IN THE INNER CITY:
http://www.med.harvard.edu/chge/green.pdf

CONSERVATION SOLUTION STRATEGIES:
http://living-room.org/sustain/altdrive.htm
http://groups.yahoo.com/group/Paleontology_and_Climate_Articles/message/486
Madison IMC: http://madison.indymedia.org/
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