As if the carbon dioxide emissions from motor vehicle operations 
aren't bad enough, here are some other environmental bads that come 
from automobile driving and other combustion sources:

[Particulate matter is a mixture of tiny particles, including dust and 
droplets of liquid in the air, generated mostly by vehicle exhaust and 
other industrial processes. The smallest of the particles, PM 2.5, is 
measured in micrograms per cubic meter; it is less than 2.5 microns in 
diameter and invisible to the human eye.]

I saw this report aired on the local news last night (Channel 15).

Mike Neuman

--------------------------------------
EcoWellness: Pollution and the heart
Jan. 31, 2007
By CHRISTINE DELL'AMORE

WASHINGTON, Jan. 31 (UPI) -- A new study that shows a powerful 
connection between particulate pollution and the risk of 
cardiovascular disease and death should motivate policymakers and 
health officials to limit Americans' exposure to air pollution, a 
burgeoning public-health danger.

Researchers at the University of Washington in Seattle have found 
postmenopausal women living in U.S. cities and exposed to average 
levels of fine particulate matter pollution, or PM 2.5, were 
drastically more at risk for getting cardiovascular disease and dying 
from its complications. 

The study, which will appear Feb. 1 in the New England Journal of 
Medicine, is the largest study of its kind and the first to evaluate 
the effects of air pollution on new cases of cardiovascular disease in 
healthy subjects. It's also the first to examine local air-pollution 
levels within a city -- by taking data from several air-quality 
monitors in different neighborhoods of one city -- rather than 
comparing rates between cities, which is considered a less accurate 
measure.

The study underscores the need for research on the health effects of 
pollution and for more pollution prevention, lead author Dr. Joel 
Kaufman, a professor of environmental health and medicine at the 
university, told United Press International. 

Kaufman and colleagues studied 65,893 women who lived in 36 U.S. 
cities from 1994 to 1998 and followed them for an average of six 
years. The women did not have previous histories of cardiovascular 
problems. The data came from the Women's Health Initiative, a major 
federal effort to investigate health outcomes in women, who have been 
long neglected in medical research. The researchers measured each 
woman's exposure to air pollutants by getting data from a pollution 
monitor closest to her ZIP code. 

Over the follow-up period 1,816 women had one or more fatal or non-
fatal cardiovascular or cerebrovascular events, such as coronary heart 
disease, heart attacks and stroke.

Particulate matter is a mixture of tiny particles, including dust and 
droplets of liquid in the air, generated mostly by vehicle exhaust and 
other industrial processes. The smallest of the particles, PM 2.5, is 
measured in micrograms per cubic meter; it is less than 2.5 microns in 
diameter and invisible to the human eye.

The metropolitan areas tested in Kaufman and colleagues' study 
generally had average levels of PM pollution, from about 4 to 20 
micrograms per cubic meter. 

But with each increase of 10 micrograms per cubic meter there was a 24-
percent increase in the risk of a cardiovascular event among the study 
subjects and a 76-percent rise in the risk of death, the researchers 
found. 

The team also noted differences in PM concentrations throughout 
various areas of a city. These fluctuations also translated to higher 
or lower health risks for the women, based on where they lived.

The researchers corrected for age, race, smoking status, educational 
level, household income and other markers that could skew the results. 

However, the study was not a true experiment, and it's not possible to 
say for sure whether air pollution causes cardiovascular problems.

Likewise, the measurements of air pollution were not exact, despite 
being more localized than other studies, and it's unknown where some 
women spent more time in traffic or indoors. The researchers also were 
not able to measure short-term exposures to PM. How short-term and 
long-term exposures differ is still being studied.

PM can travel into the deepest areas of the lungs when inhaled, and 
exposure has been linked in past studies to several health conditions, 
from aggravated asthma to premature death in people with heart and 
lung disease, according to the Environmental Protection Agency. 

Most research has targeted PM 2.5, which is believed to be most 
detrimental to health. Although the link between PM exposure and heart 
problems is not well understood, some scientists suspect the particles 
encourage hardening of the arteries, a forerunner to heart disease. 
Kaufman told UPI his next research will focus on this question.

In 2006 the EPA, which is charged with setting PM standards to protect 
public health, made a series of revisions to its national air-quality 
standards. The standards were based on data from an ongoing, colossal 
research initiative to study the health effects of particulate matter. 
In 1997 the EPA recruited thousands of peer-reviewed epidemiologic 
studies on PM 2.5 and PM 10, the coarser particles, in the United 
States and Canada. 

Many of these studies have reported a connection between lung cancer 
and particulate matter, and observed a spike in sudden heart-attack 
deaths in people exposed to the pollutants. 

The California Children's Health Study showed PM 2.5 exposure was 
linked to a slowing of lung growth in children, which compromised the 
lungs' long-term function. The research found both long-term and short-
term exposure to fine particles is associated with sickness and death. 

A follow-up to one major study, Harvard's Six Cities, suggested a 
reduction in PM 2.5 levels subsequently lowers a person's long-term 
risk of death.

A 2006 study in the Journal of the American Medical Association found 
short-term exposure to PM 2.5 can increase hospitalization of older 
adults suffering from heart and respiratory problems.

The new study led by Kaufman "is going to be a landmark study," said 
Dr. Ralph Delfino, an associate professor and epidemiologist at the 
University of California-Irvine. What's most telling, he says, is the 
magnitude of the associations between PM exposure and cardiovascular 
troubles were much larger than found in previous studies.

Delfino was also impressed by the careful collection of air-pollution 
data within cities, as most studies have relied on between-city 
comparisons. By gathering data from the nearest air-pollution monitor 
where a woman lived, the researchers were able to reduce "exposure 
error," or the tendency to ascribe a type of exposure to every 
resident in a city.

"The very robust contrast of between-city and within-city associations 
really suggests we need to look at effects at a smaller spatial scale, 
even down to where you live and work," Delfino said. Capturing 
exposures in finer detail will inform better policies and standards 
for controlling PM. Public-health agencies such as the National 
Institute for Environmental Health Sciences are committed to improving 
ways to measure exposure, Delfino pointed out.

The Women's Health Initiative data also gave the researchers a wealth 
of details about the women's physical qualities and behaviors, an 
improvement upon previous studies that had to rely on gross measures 
of study populations, said Dr. Russell Luepker, a Mayo professor at 
the University of Minnesota School of Public Health in Minneapolis.

As a growing momentum toward more regulation of PM pollution takes 
shape, many in industry ask the question, "Where's the proof?" said 
Luepker. "Studies like this answer that question." 

The study makes it clear that at the current standards for PM 
pollution, Americans continue to be at risk for cardiovascular 
problems and even death, Delfino said.

"The current regulations are seemingly inadequate to protect us," he 
added.

Copyright 2007 by United Press International. All Rights Reserved.
http://www.sciencedaily.com/upi/index.php?feed=Science&article=UPI-1-
20070131-17571900-bc-ecowellness-women.xml

Related Studies:

Exposure To Fine Particle Air Pollution Linked With Risk Of 
Respiratory And Cardiovascular Diseases, March 8, 2006 
http://www.sciencedaily.com/releases/2006/03/060308084559.htm

Air Pollution Linked To Heart Attack, Sept. 26, 2005 
http://www.sciencedaily.com/releases/2005/09/050926074103.htm

Living Near A Highway Affects Lung Development In Children, Jan. 29, 
2007 
http://www.medicalnewstoday.com/medicalnews.php?newsid=61700

Air Pollution Linked to Lung Cancer, Sept. 19, 2006 
http://www.cancerherald.com/682-air-pollution-linked-to-lung-cancer

Breast-Cancer Risk Linked to Exposure to Traffic Emissions at 
Menarche, First Birth
http://www.buffalo.edu/news/fast-execute.cgi/article-page.html?
article=72710009



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