On 05/05/2014 02:12 PM, Cook, Malcolm wrote:
On 05/05/2014 01:00 PM, Cook, Malcolm wrote:
  >> Wondering,
  >>
  >> Is it too off the beaten track to expect
  >>
  >> `mcols<-`(x,NULL)
  >
  >   > args(`mcols<-`)
  >   function (x, ..., value)
  >
  >Arguments after the ellipsis must be named:
  >
  >   `mcols<-`(x, value=NULL)

Herve - Great - of course - so - does this not provide the means requested by 
the original poster?

I think Tim also wanted 'x' to be downgraded to a GRanges instance,
like Julian's grangesPlain() does. We could use granges() for that.

Deciding of an idiom that can be used inline for just dropping the
mcols would be good too. `mcols<-`(x, value=NULL) is a little bit
tricky, ugly, and error prone as you noticed. These are probably
enough reasons for not choosing it as *the* idiom. Its only advantage
is that it doesn't introduce a new symbol.

H.


  >
  >Nothing we can do about this.
  >
  >Cheers,
  >H.
  >
  >>
  >> to work?
  >>
  >> hint: it does not
  >>
  >>   >-----Original Message-----
  >>   >From: bioc-devel-boun...@r-project.org 
[mailto:bioc-devel-boun...@r-project.org] On Behalf Of Hervé Pagès
  >>   >Sent: Monday, May 05, 2014 1:28 PM
  >>   >To: Kasper Daniel Hansen; Michael Lawrence
  >>   >Cc: Johnston, Jeffrey; ttri...@usc.edu; bioc-devel@r-project.org; 
bioconduc...@r-project.org
  >>   >Subject: Re: [Bioc-devel] [BioC] granges() method for GenomicRanges 
objects akin to ranges()...
  >>   >
  >>   >Hi,
  >>   >
  >>   >I have no problem using granges() for that. Just to clarify:
  >>   >   (a) it would propagate the names()
  >>   >   (b) it would drop the metadata()
  >>   >   (c) the mcols() would propagate only if 'use.mcols=TRUE' was
  >>   >       specified ('use.mcols' is FALSE by default)
  >>   >   (d) it would return a GRanges *instance* i.e. input object 'x'
  >>   >       would be downgraded to GRanges if it extends GRanges
  >>   >
  >>   >@Kasper: granges() on SummarizedExperiment ignores the 'use.mcols'
  >>   >arg and always propagates the mcols. Alternatively you can use rowData()
  >>   >which also propagates the mcols. granges() is actually just an alias
  >>   >for rowData() on SummarizedExperiment objects.
  >>   >
  >>   >H.
  >>   >
  >>   >
  >>   >On 05/05/2014 10:31 AM, Kasper Daniel Hansen wrote:
  >>   >> I agree with Michael on this.
  >>   >>
  >>   >> I can see why, in some usage cases, granges() is convenient to have 
with
  >>   >> use.mcols=FALSE (which seems to have been added in the latest 
release).
  >>   >>   But in my usage of granges(), where I call granges() on objects like
  >>   >> SummarizedExperiments and friends, I have been expecting granges() to 
give
  >>   >> me the GRange component of the object.  Not a crippled version of the
  >>   >> GRange component.
  >>   >>
  >>   >> This is - to me - very counter intuitive and I wish I had seen this
  >>   >> earlier.  It is particular frustrating that this default is part of 
the
  >>   >> generic.
  >>   >>
  >>   >> Best,
  >>   >> Kasper
  >>   >>
  >>   >>
  >>   >> On Mon, May 5, 2014 at 12:11 PM, Michael Lawrence 
<lawrence.mich...@gene.com
  >>   >>> wrote:
  >>   >>
  >>   >>> In my opinion, granges() is not very clear as to the intent. The 
mcols are
  >>   >>> part of the GRanges, so why would calling granges() drop them? I 
think we
  >>   >>> want something similar to unclass(), unname(), etc. This why I 
suggested
  >>   >>> dropmcols().
  >>   >>>
  >>   >>>
  >>   >>>
  >>   >>>
  >>   >>> On Mon, May 5, 2014 at 8:17 AM, Tim Triche, Jr. <tim.tri...@gmail.com
  >>   >>>> wrote:
  >>   >>>
  >>   >>>> That's exactly what I was after -- the generic is already defined, 
so why
  >>   >>>> not use it?
  >>   >>>>
  >>   >>>> --t
  >>   >>>>
  >>   >>>>> On May 5, 2014, at 7:42 AM, Julian Gehring <julian.gehr...@embl.de>
  >>   >>>> wrote:
  >>   >>>>>
  >>   >>>>> Hi,
  >>   >>>>>
  >>   >>>>>> On 05.05.2014 16:22, Martin Morgan wrote:
  >>   >>>>>> generalize as setMcols, like setNames? setMcols(x, NULL)
  >>   >>>>>
  >>   >>>>> How about Tim's original suggestion, to add a 'granges' method that
  >>   >>>> works on a 'GRanges' input?  The current definition
  >>   >>>>>
  >>   >>>>> granges(x, use.mcols=FALSE, ...)
  >>   >>>>>
  >>   >>>>> seem suited for this.
  >>   >>>>>
  >>   >>>>> Best wishes
  >>   >>>>> Julian
  >>   >>>>
  >>   >>>
  >>   >>>          [[alternative HTML version deleted]]
  >>   >>>
  >>   >>> _______________________________________________
  >>   >>> Bioc-devel@r-project.org mailing list
  >>   >>> https://stat.ethz.ch/mailman/listinfo/bioc-devel
  >>   >>>
  >>   >>
  >>   >>   [[alternative HTML version deleted]]
  >>   >>
  >>   >> _______________________________________________
  >>   >> Bioc-devel@r-project.org mailing list
  >>   >> https://stat.ethz.ch/mailman/listinfo/bioc-devel
  >>   >>
  >>   >
  >>   >--
  >>   >Hervé Pagès
  >>   >
  >>   >Program in Computational Biology
  >>   >Division of Public Health Sciences
  >>   >Fred Hutchinson Cancer Research Center
  >>   >1100 Fairview Ave. N, M1-B514
  >>   >P.O. Box 19024
  >>   >Seattle, WA 98109-1024
  >>   >
  >>   >E-mail: hpa...@fhcrc.org
  >>   >Phone:  (206) 667-5791
  >>   >Fax:    (206) 667-1319
  >>   >
  >>   >_______________________________________________
  >>   >Bioc-devel@r-project.org mailing list
  >>   >https://stat.ethz.ch/mailman/listinfo/bioc-devel
  >>
  >
  >--
  >Hervé Pagès
  >
  >Program in Computational Biology
  >Division of Public Health Sciences
  >Fred Hutchinson Cancer Research Center
  >1100 Fairview Ave. N, M1-B514
  >P.O. Box 19024
  >Seattle, WA 98109-1024
  >
  >E-mail: hpa...@fhcrc.org
  >Phone:  (206) 667-5791
  >Fax:    (206) 667-1319


--
Hervé Pagès

Program in Computational Biology
Division of Public Health Sciences
Fred Hutchinson Cancer Research Center
1100 Fairview Ave. N, M1-B514
P.O. Box 19024
Seattle, WA 98109-1024

E-mail: hpa...@fhcrc.org
Phone:  (206) 667-5791
Fax:    (206) 667-1319

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