I'll back-track on my advice a little, and say that the right way to enable the user to get reproducible results is to respect the setting the user makes outside your function. So for
your = function() unlist(bplapply(1:4, rnorm)) The user will register(MulticoreParam(2, RNGseed=123)) your() to always produces the identical result. Following Aaron's strategy, the R-level approach to reproducibility might be along the lines of - tell the user to set parallel::RNGkind("L'Ecuyer-CMRG") and set.seed() - In your function, generate seeds for each job n = 5; seeds <- vector("list", n) seeds[[1]] = .Random.seed # FIXME fails if set.seed or random nos. have not been generated... for (i in tail(seq_len(n), -1)) seeds[[i]] = nextRNGStream(seeds[[i - 1]]) - send these, along with the job, to the workers, setting .Random.seed on each worker bpmapply(function(i, seed, ...) { oseed <- get(".Random.seed", envir = .GlobalEnv) on.exit(assign(".Random.seed", oseed, envir = .GlobalEnv)) assign(".Random.seed", seed, envir = .GlobalEnv) ... }, seq_len(n), seeds, ...) The use of L'Ecuyer-CMRG and `nextRNGStream()` means that the streams on each worker are independent. Using on.exit means that, even on the worker, the state of the random number generator is not changed by the evaluation. This means that even with SerialParam() the generator is well-behaved. I don’t know how BiocCheck responds to use of .Random.seed, which in general would be a bad thing to do but in this case with the use of on.exit() the usage seems ok. Martin On 12/31/18, 3:17 PM, "Lulu Chen" <luluc...@vt.edu> wrote: Hi Martin, Thanks for your help. But setting different number of workers will generate different results: > unlist(bplapply(1:4, rnorm, BPPARAM=SnowParam(1, RNGseed=123))) [1] 1.0654274 -1.2421454 1.0523311 -0.7744536 1.3081934 -1.5305223 1.1525356 0.9287607 -0.4355877 1.5055436 > unlist(bplapply(1:4, rnorm, BPPARAM=SnowParam(2, RNGseed=123))) [1] -0.9685927 0.7061091 1.4890213 -0.4094454 0.8909694 -0.8653704 1.4642711 1.2674845 -0.2220491 2.4505322 > unlist(bplapply(1:4, rnorm, BPPARAM=SnowParam(3, RNGseed=123))) [1] -0.96859273 -0.40944544 0.89096942 -0.86537045 1.46427111 1.26748453 -0.48906078 0.43304237 -0.03195349 [10] 0.14670372 > unlist(bplapply(1:4, rnorm, BPPARAM=SnowParam(4, RNGseed=123))) [1] -0.96859273 -0.40944544 0.89096942 -0.48906078 0.43304237 -0.03195349 -1.03886641 1.57451249 0.74708204 [10] 0.67187201 Best, Lulu On Mon, Dec 31, 2018 at 1:12 PM Martin Morgan <mtmorgan.b...@gmail.com> wrote: The major BiocParallel objects (SnowParam(), MulticoreParam()) and use of bplapply() allow fully repeatable randomizations, e.g., > library(BiocParallel) > unlist(bplapply(1:4, rnorm, BPPARAM=MulticoreParam(RNGseed=123))) [1] -0.96859273 -0.40944544 0.89096942 -0.48906078 0.43304237 -0.03195349 [7] -1.03886641 1.57451249 0.74708204 0.67187201 > unlist(bplapply(1:4, rnorm, BPPARAM=MulticoreParam(RNGseed=123))) [1] -0.96859273 -0.40944544 0.89096942 -0.48906078 0.43304237 -0.03195349 [7] -1.03886641 1.57451249 0.74708204 0.67187201 > unlist(bplapply(1:4, rnorm, BPPARAM=SnowParam(RNGseed=123))) [1] -0.96859273 -0.40944544 0.89096942 -0.48906078 0.43304237 -0.03195349 [7] -1.03886641 1.57451249 0.74708204 0.67187201 The idea then would be to tell the user to register() such a param, or to write your function to accept an argument rngSeed along the lines of f = function(..., rngSeed = NULL) { if (!is.null(rngSeed)) { param = bpparam() # user's preferred back-end oseed = bpRNGseed(param) on.exit(bpRNGseed(param) <- oseed) bpRNGseed(param) = rngSeed } bplapply(1:4, rnorm) } (actually, this exercise illustrates a problem with bpRNGseed<-() when the original seed is NULL; this will be fixed in the next day or so...) Is that sufficient for your use case? On 12/31/18, 11:24 AM, "Bioc-devel on behalf of Lulu Chen" <bioc-devel-boun...@r-project.org on behalf of luluc...@vt.edu> wrote: Dear all, I posted the question in the Bioconductor support site ( https://support.bioconductor.org/p/116381/ <https://support.bioconductor.org/p/116381/>) and was suggested to direct future correspondence there. I plan to generate a vector of seeds (provided by users through argument of my R function) and use them by set.seed() in each parallel computation. However, set.seed() will cause warning in BiocCheck(). Someone suggested to re-write code using c++, which is a good idea. But it will take me much more extra time to re-write some functions from other packages, e.g. eBayes() in limma. Hope to get more suggestions from you. Thanks a lot! Best, Lulu [[alternative HTML version deleted]] _______________________________________________ Bioc-devel@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/bioc-devel <https://stat.ethz.ch/mailman/listinfo/bioc-devel> _______________________________________________ Bioc-devel@r-project.org mailing list https://stat.ethz.ch/mailman/listinfo/bioc-devel