Hi,
I've found a working solution but not sure whether it's the best one, but
could be useful for those who have similar interest :
rfq.sf1=append(rfq.sf1[*-n.sf.ids*],rfq.phix1[*n.ph.ids*])
Regards,
Ramzi

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On Fri, Feb 5, 2010 at 11:53 AM, Ramzi TEMANNI <[email protected]>wrote:

> Hi,
> I'm trying to generate simulated  fastq data by mixing read from original
> sample with Phix reads
> So i load my sample data and phix data
> library(ShortRead)
> rfq.sf1<- readFastq(dir, pattern=sample.f1)
> rfq.phix1 <- readFastq(dir, pattern=phix.f2)
> specify the percentage of reads in the original file to be replaced by phix
> reads and select ramdomly the reads to be replaced in sample and the reads
> to be selected in phix
> nbreads=fx.ratio/100*length(rfq.sf1)
> n.sf.ids=sample(1:length(rfq.sf1),nbreads)
> n.ph.ids=sample(1:length(rfq.phix1),nbreads)
> but when I call
> rfq.sf1[n.sf.ids]=rfq.phix1[n.ph.ids]
> I get an error
> Error in rfq.sf1[n.sf.ids] = rfq.phix1[n.ph.ids] :
>   object of type 'S4' is not subsettable
> I tried then
> sread(rfq.sf1[n.sf.ids])=sread(rfq.phix1[n.ph.ids])
> quality(rfq.sf1[n.sf.ids])=quality(rfq.phix1[n.ph.ids])
> And i get an error too
> Error in sread(rfq.sf1[n.sf.ids]) = sread(rfq.phix1[n.ph.ids]) :
>   could not find function "sread<-"
> Error in quality(rfq.sf1[n.sf.ids]) = quality(rfq.phix1[n.ph.ids]) :
>   could not find function "quality<-"
> what will be the method to use to replace theses reads ?
> Thanks in advance for suggestions.
>
>
> Kind regards
> Ramzi
> ----------------------------------------------------------------
>

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