Hi Martin,

Using the ShortRead package, for files > 6.5 Gb size, I seem to be running into this error using the readFastq function:

Error in .Call(.read_solexa_fastq, src, withIds) :
 negative length vectors are not allowed

If this is memory related - is there a work-around to working with the entire file?

Thank You,
Sirisha

> sessionInfo()
R version 2.10.1 (2009-12-14)
x86_64-unknown-linux-gnu

locale:
[1] C

attached base packages:
[1] stats graphics grDevices utils datasets methods base
other attached packages:
[1] ShortRead_1.4.0 lattice_0.17-26 BSgenome_1.14.2 Biostrings_2.14.12 [5] IRanges_1.4.11
loaded via a namespace (and not attached):
[1] Biobase_2.6.1 grid_2.10.1   hwriter_1.1

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