On Wed, Mar 31, 2010 at 3:55 AM, David Rossell <
[email protected]> wrote:

> Following a recent thread, I also have found convenient to store nextgen
> data as RangedData instead of ShortRead objects. They require far less
> memory and make feasible working with several samples at the same time (in
> my 8Gb RAM desktop I can load 2 ShortRead objects at the most, with
> RangedData I haven't struck the upper limit yet).
>
> I am thinking about taking this idea a step forward: RangedDataList allows
> storing info from several samples (e.g. IP and control) in a single object.
> The only problem is RangedDataList does not store information about the
> samples, e.g. the phenoData we're used to in ExpressionSet objects. My idea
> is to define something like a "SequenceSet" class, which would contain a
> RangedDataList with the ranges, a phenoData with sample information, and
> possibly also information about the experiment (e.g. with the MIAME analog
> for sequencing, MIASEQE).
>
> The thing is I don't want to re-invent the wheel. I haven't seen that this
> is implemented yet, but is someone working on it? Any criticism/ ideas?
>
>
RangedDataList already supports this. See the 'elementMetadata' and
'metadata' slots in the Sequence class.

Michael



> Best,
>
> David
>
> --
> David Rossell, PhD
> Manager, Bioinformatics and Biostatistics unit
> IRB Barcelona
> Tel (+34) 93 402 0217
> Fax (+34) 93 402 0257
> http://www.irbbarcelona.org/bioinformatics
>
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