On Thu, 6 Jan 2011, Laurent Gautier wrote:

On 1/6/11 1:08 AM, Gordon K Smyth wrote:
Dear Kristen and Laurent,

A possible (likely) explanation for the error is that your design matrix isn't of full column rank. Can you please check this:

  library(limma)
  is.fullrank(design)
Thanks. It was the case here.
Future versions of estimateCRDisp() could test that and report an informative error message.

Yes, done.
Gordon

Best,
Laurent

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