Hi Hans-Ulrich,

thanks for your prompt answer. Any chance you could give an approximate 
timeshift for this upgrade? I am very interested in that, I wonder if you could 
keep me posted. I will also keep an eye on the package webpage for any updates.

Best,

Dave

> Date: Wed, 16 Feb 2011 18:02:18 +0100
> From: [email protected]
> To: [email protected]
> Subject: Re: [Bioc-sig-seq] R453Plus1Toolbox
> 
> Hi Dave,
> 
> that is right. The manual of Roche's AVA software says: "The automatic 
> Variant detection does not currently report insertions or monomer 
> deletions shorter than 3 bases." At this time, the R453Plus1Toolbox does 
> not implement an indel calling algorithm but relies on the results 
> reported by the AVA software.
> Since it seems that Roche is not going to solve this issue, we have this 
> topic on our to-do list for our package.
> 
> Best,
> Hans-Ulrich
> 
> 
> On 16/02/11 13:43, David A. wrote:
> > Hi, I have found a package called R453Plus1Toolbox for analysis of Roche's 
> > sequencing data. As far as I know, using AVA, 1bp indels are filtered off 
> > fro mthe results to avoid false positives. They can be seen by going to the 
> > flowgrams of the region, but they are not part of the output table. Does 
> > anyone know if R453Plus1Toolbox can detect them?
> >
> > Thanks,
> >
> > Dave
> >                                     
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> >
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> 
> 
> -- 
> Hans-Ulrich Klein
> Institute of Medical Informatics
> University of Münster
> Domagkstraße 9
> 48149 Münster, Germany
> Tel.: +49 (0)251 83-58405
> 
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