Hi,

>> what is meant by "the parsing is lazy" exactly? 
> I don't know, did I use that term?

Yes, in the docs
http://hackage.haskell.org/package/blastxml-0.3.1/docs/Bio-BlastXML.html

>> You want a BlastResult with a lazy list of results
>> (containing BlastRecords with a lazy list of hits, etc)?
> 
> No - that is the case now, but I generally just discard the top
> BlastResult "node", and extract the results -- as a lazy list.

what is the typical usage pattern of that list?

if (memory) space is very tight, then the result of the parse
could just be a list of file offsets, to be used later,
when elements are accessed.

NB: There's also
http://hackage.haskell.org/package/xml-conduit-1.2.0.2/docs/Text-XML-Stream-Parse.html
(parseBytes)  (haven't used it,
but Snoyman's libraries are generally well-optimized for performance.)

NB: ignoring that it's about Haskell - what do you want the OS to do?
mmap the whole file? (
http://stackoverflow.com/questions/258091/when-should-i-use-mmap-for-file-access
)
Can this be done with some Haskell library?

- J.

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