Dear All, 

I'm looking for an implementation of Smith and Waterman algorithm to use in the 
Java desktop application I want to develop. 

I did find some information on pairwise aligners but what I would ideally want 
to have is something similar to the SSEARCH package that can perform alignments 
against a very big databases, saved locally in a fasta format. Speed is quite 
important and ideally I would need an output that I can easily parse, 
identifying mismatch/gap positions etc.

Any suggestions if there is any java implementation that would fit the 
description? I will be working on short sequences so sensitivity is crucial. 

Thanks very much for your help,
Peter
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