Kreatech Biotechnology Launches a Series of ULS arrayCGH Labeling
Kits Array Based Comparative Genomic Hybridization (CGH) Analysis
AMSTERDAM,
New "ULS(TM) arrayCGH Labeling Kits" for Direct, Non-enzymatic
labeling of genomic DNA for microarray based comparative genomic
hybridization (arrayCGH) analysis
Kreatech Biotechnology BV announces the launch of a series of ULS
arrayCGH labeling kits offering its' proprietary ULS labeling
molecule bound to a choice of fluorescent dye pairs that have been
licensed by Kreatech including dyes from GE Healthcare/Amersham
(CyDyes), Perkin Elmer (Cyanine Dyes) and Dyomics (DYDyes). The
complete labeling kits include unique purification columns
(KREApure), blocking buffer (KREAblock) and hybridization buffers.
The ULS labeling of nucleic acids is a robust, one-step
procedure that is completed within 30 minutes. "The possibility of
analyzing genomic DNA directly without the need to amplify is a very
attractive feature to many researchers, not only does it save time
but it also removes the potentially biasing enzymatic step that is
currently required in order to label genomic samples" according to
Ted van der Lende, Director of product development.
The Universal Linkage System - ULS(TM) - is a proprietary
labeling technology that has been optimized for arrayCGH analysis on
DNA arrays. The ULS arrayCGH labeling kit has the unique feature of
allowing the user to label genomic DNA directly in a one step
labeling reaction (30 minutes), avoiding the need for a potentially
biasing enzymatic step. This results in more accurate data as well
as saving time and money. The ULS labeling efficiency is independent
of fragment length making it ideal for use with archival DNA. Where
samples are limiting and amplification is required, this is carried
out using natural unmodified nucleotides which is then followed by
the one step ULS labeling.
Brent Keller, acting Commercial Director for Kreatech states "Our
decision to make available arrayCGH labeling kits that offers a
choice of fluorescent dye pairs from the leading dye manufacturers
is consistent with our strategy to offer ULS technology independent
of array platform used and the labels that researchers work with. In
this way, ULS can be the ubiquitous choice of researchers for their
labeling needs, eliminating the concern over matching arrays and
labels with the offering of every manufacturer."
Kreatech earlier this year launched a line of aRNA labeling kits
for expression arrays with dye pairs from GE Healthcare, Perkin
Elmer, Dyomics and a Biotin system for Affymetrix users.
For more information on the ULS labeling kits visit
http://www.kreatech.com
SOURCE Kreatech Biotechnology B.V.
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