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Kreatech Biotechnology Launches PlatinumBright(TM) Nucleic Acid 
Labeling Kits for In Situ Hybridization and Filter Hybridization 
Applications



Kreatech Biotechnology BV announces the launch of a series of 
PlatinumBright nucleic acid labeling kits offering its' proprietary 
ULS labeling molecule bound to a choice of fluorescent dyes or 
haptens, The complete general nucleic acid labeling kits include 
unique purification columns (KREApure) which ensure the complete 
removal of unreacted dye while yielding very high sample recovery 
that is independent of fragment length. 

The Universal Linkage System - ULS(TM) - is a proprietary labeling 
technology that has been engineered to give very reproducible 
labeling densities, both inter- and intra-experimental protocols, 
without the use of enzymes that can cause biases. While the labeling 
in the PlatinumBright kits have been designed to provide the optimal 
labeling density for Fluorescent in situ hybridization (FISH) 
applications, the ULS labeling reaction in these kits are also 
optimal for filter hybridizations such as Northern Blots, Southern 
Blots, Spot Blots and Dot Blot hybridizations as well as use with 
Tissue Arrays and ChIP on Chip experiments (labeling of promoter 
fragments after Chromatin immuno precipitation). 

ULS labeling of nucleic acids is a robust, one-step procedure that 
is completed within 30 minutes. "The PlatinumBright nucleic acid 
labeling kits offer the researcher the possibility to non 
enzymatically label their target nucleic acid of choice, with a 
choice of six commonly used dyes and a biotin kit and then proceed 
to use this labeled material in several hybridization applications. 
Our decision to make available the PlatinumBright general nucleic 
acid labeling kits is consistent with our strategy to offer ULS 
technology to researchers who have labeling needs for a variety of 
nucleic acid applications. End users using PlatinumBright kits can 
now very easily, quickly, and reproducibly label nucleic acids for 
whatever application they can think of", according to Brent Keller, 
General Manager/VP Commercial Operations for Kreatech. 

Kreatech earlier this year launched a line of aRNA labeling kits for 
expression arrays with dye pairs from GE Healthcare, Perkin Elmer, 
Dyomics, and a Biotin system for Affymetrix users as well as a line 
of arrayCGH labeling kits with the same dye pairs for the direct 
labeling of genomic DNA for microarray based comparative genomic 
hybridization analysis. 

For more information on all of the ULS labeling kits visit 
www.kreatech.com 







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