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Southeast Nebraska Cancer Center Receives Major Research Funding
Tuesday December 20, 9:30 am ET 


LINCOLN, Neb., Dec. 20 The U.S. Congress directed $1.5 million in 
cancer research funding to the Southeast Nebraska Cancer Center as 
part of the Department of Defense appropriations for the current 
fiscal year.
 
This critical new funding will allow doctors and researchers at 
Lincoln- based Southeast Nebraska Cancer Center to develop new, more 
effective treatments for cancer patients based on their molecular 
profile. This funding is expected to be signed into law soon.

"This research will help us identify genomic sequence changes 
associated with cancer in individual patients," said Dr. Mark 
Carlson with the Southeast Nebraska Cancer Center.

"Our hope for the future is that your doctor can run a simple test 
on a small tumor sample and use a quick genetic analysis to tailor 
the best therapy for you as an individual," explains Dr. 
Carlson. "It looks increasingly promising that this form of genetic 
testing will improve development of cancer therapy and help more 
people survive cancer."

Some call this personalized medicine. This Lincoln cancer center is 
now part of a fundamentally different way to cure disease. Delving 
more deeply into the genetic origins leading to this complex set of 
diseases will help create new discoveries and tools for a new 
generation of cancer prevention, diagnostic and therapy strategies.

"Cancer is a very complex disease that will kill over 560,000 
Americans this year," explains Rep. Jeff Fortenberry, R-Neb. "This 
research will link cancer research around the country and 
potentially revolutionize the diagnosis, treatment and prevention of 
cancer," Fortenberry said in announcing the research funding. Both 
U.S. Senator Chuck Hagel and Sen. Ben Nelson worked closely with 
Rep. Fortenberry to bring this research funding to Nebraska.

"We are pleased that Nebraska will help explore how physicians can 
use this information to save lives. It is a great opportunity for 
our local medical community to work together on new ideas in cancer 
therapy. For the seriously ill, we will create access to the latest 
research ideas in a hometown setting," Fortenberry adds.

The funding is part of an ongoing Department of Defense technology- 
transfer initiative. This program is aimed at moving dual-use 
discoveries and medical treatments more rapidly into society, so 
both the military and the public benefit from government research. 
In this case, the Southeast Nebraska Cancer Center will be part of 
the U.S. Department of Defense's National Functional Genomics Center.

The Southeast Nebraska Cancer Center will use the funds to create a 
local network to collect cancer tissue samples from patients and 
follow these patients' progress through therapy. Information will be 
merged into a massive nationwide database that will help physicians 
make personalized cancer treatment decisions.

This large-scale effort combines government, academic and private-
sector resources. The program also uses a "systems biology" approach 
that brings together advanced science in pharmaceuticals, molecular 
biology, genetic screening, bio-informatics systems and other 
technology.

"This program will be very meaningful in Nebraska," adds Tracy 
Christianson, Director of Research, Southeast Nebraska Cancer 
Center. "The latest figures indicate that more than 8,000 new cases 
of invasive cancer will be diagnosed among our state's citizens. 
Sadly, we will experience nearly 3,500 deaths, based on these 
estimates. Cancer is the second-leading cause of death in Nebraska, 
after heart disease. This research will help us make faster progress 
in solving a critical health issue for our state and our country."

While great strides have been made in cancer research, says 
Christianson, more must be done. "We can now study tens of thousands 
of variations at a time, rather than focus on single genes. We can 
open new frontiers in medical knowledge for new cures, faster, and 
more effectively than ever before," she added.

The Southeast Nebraska Cancer Center is a unique participant in this 
program, Christianson adds.

"The other participants are large medical research institutions 
around the country," she explains. "Our center is the only local 
physician's clinic in the program. We are the pioneer in launching 
this diagnostic innovation into a local medical community. What we 
learn will be the model nationally."

The Southeast Nebraska Cancer Center has an active clinical research 
program, she says. This made it an ideal candidate to be the first 
local community based center to participate in the program.

"Our main goal in doing clinical trials is to offer our patient's 
the latest options in cancer treatment. Our clinical study program 
matches very well with this effort to implement the latest 
innovations in using genetics to diagnose the most effective 
treatment alternatives."




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Source: Southeast Nebraska Cancer Center


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