On Mon, May 17, 2010 at 12:58 PM, Ola Spjuth <[email protected]> wrote:
> Hi,
> I asked this question
> on http://blueobelisk.shapado.com/questions/is-there-a-chemical-ontology-which-i-can-use-to-annotate-my-chemical-reactions
> but I am not sure that it reaches everyone (hence the double-posting).
> Basically what I am after is to classify a set of reactions and I would like
> to use a chemical ontology (or controlled vocabulary) rather than making up
> my own reaction-type-names (such as "n-dealkylation", "s-dealkylation" etc).
> Could anyone maybe recommend such an ontology?
> Cheers,


We published an ontology in the CMLReact paper

J Chem Inf Model. 2006 Jan-Feb;46(1):145-57.

Chemical markup, XML, and the world wide web. 6. CMLReact, an XML
vocabulary for chemical reactions.
Holliday GL, Murray-Rust P, Rzepa HS.

http://pubs.acs.org/doi/pdf/10.1021/ci0502698 (cost 30USD for 48 hours
if you don't subscribe)

The ontology was taken from IUPAC sources and rendered in XML (we
would do this differently now).

We are currently extracting reactions from the literature and will
hope to present a phenomenological ontology

I don't think there will be a single approach that satisfies everyone
and we shall need multiple ontologies.

P.



> /Ola
> --
> Ola Spjuth, PhD
> Department of Pharmaceutical Biosciences
> Box 541, Uppsala University
> Sweden
> Email: [email protected]
> Web: http://www.farmbio.uu.se
> Bioclipse: http://www.bioclipse.net
>
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-- 
Peter Murray-Rust
Reader in Molecular Informatics
Unilever Centre, Dep. Of Chemistry
University of Cambridge
CB2 1EW, UK
+44-1223-763069

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