>From one of my ejournal services:

Severe Acute Respiratory Syndrome (SARS) Update:
Friday, March 28, 2003
Medscape Medical News 2003. � 2003 Medscape 
Craig Sterritt, Editor, Medscape Infectious Diseases

"Scientists at the University of Hong Kong announced
yesterday that they have developed a diagnostic test
to rapidly identify cases of severe acute respiratory
syndrome (SARS). The researchers also announced that
they had confirmed a coronavirus as the cause of SARS.
Confident of their findings, the team recommended that
SARS, a provisional name for the disease, be renamed
"coronavirus pneumonia" or CVP. 

"Epidemiology: The World Health Organization (WHO)
cumulative tallies of suspected SARS cases and deaths
are now 1,408 and 53, respectively. These daily
counts, reported on March 27, include 85 new cases and
4 new deaths compared with the previous day. Romania
was added to WHO's list of affected countries today,
with 3 suspected cases identified there. 

"The U.S. Centers for Disease Control and Prevention
(CDC) is now reporting a total of 51 suspected U.S.
cases in 21 states, up from 45 cases on March 26. 

"On March 26, Chinese authorities officially reported
a total of 792 SARS cases and 31 deaths that occurred
in 7 cities of Guangdong Province between November 16,
2002, and February 28, 2003. WHO is presently
reporting a total of 806 suspected SARS cases and 34
deaths in mainland China. 

"Health officials in Singapore have quarantined 861
people with flu-like symptoms and have closed all
schools until April 6. A total of 78 SARS cases and 2
deaths have been reported there. 

"More than 1,000 people were quarantined and schools
were ordered closed in Hong Kong late yesterday. This
followed the identification of 51 new SARS cases and a
warning by a top health official that SARS was
spreading among the general public. 

"Health officials in the U.S. and elsewhere, however,
continue to stress that transmission of SARS appears
to require close and prolonged contact, as among case
patients and healthcare workers and case patients and
family members. 

"Etiology: Scientists at the University of Hong Kong
announced on March 27 that they have confirmed a
coronavirus as the cause of SARS. The CDC announced
Monday that a new coronavirus was the prime suspect in
the search for the cause of SARS. Julie Gerberding,
MD, director of the CDC, stated that the detected
virus did not appear to be a known coronavirus. "We
know from sequencing pieces of the virus DNA that it
is not identical to the coronaviruses that we have
seen in the past. This may very well be a new or
emerging coronavirus infection, but it is very
premature to assign a cause." 

"Diagnosis, Treatment, Outcomes: Scientists at the
University of Hong Kong announced yesterday that they
have developed a diagnostic test to rapidly identify
SARS cases. The test is based on polymerase chain
reaction (PCR) technology. So far, test results in
confirmed SARS cases have been consistently positive,
while healthy controls have consistently tested
negative. Another test, an immunofluorescence assay,
is also in development. 

"In a "virtual grand rounds" on clinical features and
treatment of SARS organized by WHO on Wednesday,
clinicians managing SARS patients described disease
features at presentation, treatment, progression,
prognostic indicators, and discharge criteria. There
was general consensus that no specific therapy
demonstrated any particular effectiveness. According
to a summary of the proceedings distributed by the
ProMED email program of the International Society for
Infectious Diseases, participating clinicians agreed
"that a subset of SARS patients, perhaps 10 percent,
decline and need mechanical assistance to breathe.
These people often have other illnesses that
complicate their care. In this group, mortality is
high." According to the summary, however, the majority
of patients show improvement in signs and symptoms at
day 6 or 7." 

The CDC page:
http://www.cdc.gov/ncidod/sars/

The WHO page:
http://www.who.int/csr/sars/en/ 

Debbi

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