This is a very short 'layperson' article (entirely
below); if anyone is interested, I could hunt down the
more technical one(s).  

http://my.webmd.com/content/Article/87/99548.htm?printing=true
"Sheep with scrapie may be able to pass a kind of mad
cow disease to humans, a new study shows.  Cattle get
bovine spongiform encephalopathy -- BSE or mad cow
disease -- from a dangerous prion (an abnormal form of
normal cell protein) called PrPsc. When humans eat
PrPsc in contaminated beef, it can give them the human
version of mad cow disease called variant
Creutzfeldt-Jakob disease (vCJD). Scientists say vCJV
comes from eating nerve tissue (such as that in the
brain and spinal cord) from cattle infected with mad
cow disease. 

"Sheep have their own form of the disease. It's called
scrapie -- a fatal, degenerative disease affecting the
central nervous system of sheep and goats.  Eating
meat -- which is muscle -- of sheep with scrapie is
not supposed to be dangerous to humans. But now
researchers report finding PrPsc in sheep muscle. The
findings, by Olivier Andr�oletti of the National
Veterinary School of Toulouse, France, and colleagues
appear in the May 23 advance online edition of Nature
Medicine. 

"Dietary exposure to scrapie is currently considered
nonhazardous to humans," Andr�oletti and colleagues
write. "However, the presence of PrPsc in muscles from
sheep naturally infected with scrapie calls for a
review of this question."  Making such a "review" more
urgent is the recent finding that sheep can become
infected with BSE as well as scrapie. 

"It's not clear exactly how much PrPsc-contaminated
meat a sheep would have to eat to pose a danger to
humans. Sheep have about 5,000 times less PrPsc in
their muscles than they do in their brains. And the
sheep in the Andr�oletti team's study had to eat
massive amounts of PrPsc to accumulate significant
levels of the protein in their muscles.* 

(*Note that last sentence.)

"This is the first evidence for PrPsc in muscle from
TSE-incubating animals of a species that enters the
human food chain," Andr�oletti and colleagues note. 

Debbi
*Definitely* No Sheep Eyeballs For Me Maru  >:P


        
                
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