----- Original Message ----- 
From: "Robert J. Chassell" <[EMAIL PROTECTED]>
To: <[email protected]>
Sent: Saturday, September 24, 2005 7:09 PM
Subject: Re: Brave New Genetic Frontiers


> Leonard Matusik <[EMAIL PROTECTED]> asked
>
>     How can blind cave fish could result purely from random mutations
>     ... ?
>
> Well, the word `random' is misleading since after the
> non-exact-replications, the survivors are selected to survive.
>
> The word `random' is accurate in that you cannot specify which births
> show the relevant non-exact-replications; and you cannot specify how
> many generations will pass before all the fish become blind; and you
> cannot specify how many individuals in each generation make up a
> population.  You have to do all this probabilistically.
>
> But the word is not as useful a concept as the notion of `selection'.
> Randomness makes selection more possible and efficient.
>
> You probably want to ask
>
>     How can a population of blind cave fish result from occasional
>     non-exact-replications in which a portion of those born in each
>     generation make a lower investment in unnecessary resources than
>     their competitors and are more likely to survive than their
>     competitors?
>
> I know that is a long sentence.  But the question involves
>
>     1. blind cave fish
>
>     2. non-exact-replications
>
>     3. population thinking, not individual thinking
>
>     4. many generations, each with a large enough population
>
>     5. selection for reproduction of those who are best adapted to the
>        environment at that time for survival for reproduction
>
> Off hand, I cannot think of a shorter sentence that includes all those
> concepts.
>
> It would be great if someone else can.

I think the question can be expressed.

Is the natural tendency for a population to disperse in gene space  through
random mutations (in the absence of a natural selection induced focus in
gene space) sufficient  to explain the existence of blind cave fish.

Dan M.


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