Update of bug #67921 (group groff):
Status: In Progress => Fixed
Open/Closed: Open => Closed
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Follow-up Comment #2:
I forgot to add a bug-closer to the ChangeLog entry for this, and so forgot it
in the commit message, too, and consequently to close this ticket a couple of
pushes ago.
commit ce1288a595348b48e53d52c6193cda77319fe257
Author: Norwid Behrnd <[email protected]>
Date: Tue Jan 13 17:10:53 2026 +0100
[chem]: Improve "lsd.chem" example cosmetics.
* contrib/chem/examples/lsd.chem: Improve visual representation.
Reorganize representation of the structure.
- For aesthetic appeal, the structure was a rotated little bit. Its
orientation is the one of ergoline, the parent hydride (in chemists'
terms, the senior or reference structure motive) lsd and other ergot
alkaloids derive from as displayed in appendix 3 of [1a], and
publications (e.g., [2-4]). The edit retains the pragmatic
definition of the pyrrole moiety based on keyword flatring.
- The backbone labels the rings A, B, C, and D. This is both for
backward compatibility in nomenclature (rule P-101.2.4 in [1b])
still used in peer reviewed publications today (e.g., [2-4]) as well
as showcase of chem's flexibilty of definitions coined by the user.
- Some cleaning according e.g., to rules GR-4.1.1, 4.1.2, 6.5.[5]
[1a] Nomenclature of Organic Chemistry: IUPAC Recommendations and
Preferred Names 2013; Favre, H. A., Powell, W. H., International
Union of Pure and Applied Chemistry, Eds.; Royal Society of
Chemistry: Cambridge, 2014. Authorized online excerpt:
https://iupac.qmul.ac.uk/BlueBook/Papp3.html
[1b] Same as [1a], authorized online excerpt:
https://iupac.qmul.ac.uk/BlueBook/P10.html#1010204
[2] Barker, S. A. Simple Analogs of the LSD D-Ring: A Consideration of
Structure–Activity Relationships and Their Potential as
Therapeutics. ACS Chem. Neurosci. 2025, 16 (22), 4309–4314.
https://doi.org/10.1021/acschemneuro.5c00695.
[3] Pazur, E. J.; Kalatanova, A.; Tasker, N. R.; Vainionpää, K.;
Leinonen, H.; Wipf, P. Synthesis and Biological Analysis of
Iso-Dimethyltryptamines in a Model of Light-Induced Retinal
Degeneration. ACS Med. Chem. Lett. 2024, 15 (7), 1049–1056.
https://doi.org/10.1021/acsmedchemlett.4c00130.
[4] Rathnayake, U.; Garner, P. Asymmetric Synthesis of Lysergic Acid
via an Intramolecular (3+2) Dipolar Cycloaddition/ Ring-Expansion
Sequence. Org. Lett. 2021, 23 (17), 6756–6759.
https://doi.org/10.1021/acs.orglett.1c02337.
[5] Brecher, J. Graphical Representation Standards for Chemical
Structure Diagrams (IUPAC Recommendations 2008). Pure Appl. Chem.
2008, 80 (2), 277–410.
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