Following rekado's friendly advice, I was able to downgrade guix with: guix pull --url=https://git.savannah.gnu.org/cgit/guix.git/snapshot/01049bb0c1f3f69afb8d1782f99ca5c0adaed946.tar.gz --no-substitutes
where both options (--url and --no-substitutes) were neccessary. Now, everything seems to work again: commands like `guix package -i` and `guix system reconfigure` no longer get stuck at "updating list of substitutes". Thanks, rekado. Still, I wonder * what caused this issue; * if anybody else is/was experiencing it; and * when it will be fixed in master-branch (i.e. when I will be able to `guix pull` and `guix pull` again successfully).