Hello,

I can confirm that the same problem presents itself on
  guix 9896b37
    Repository-URL: https://git.savannah.gnu.org/git/guix.git
    Branch: master
    Commit: 9896b37ac53e9b0504de55dd5ba4bfa2c241a7ed
of August 17.

A likely culprit is
commit 3481a5cb37cacbb54f74a2b1fa52ffc5c972b09f
Author: Nicolas Goaziou <m...@nicolasgoaziou.fr>
Date:   Wed Aug 9 10:45:42 2023 +0200
    guix: profiles: Do not raise error on incomplete TeX Live setups.
    * guix/profiles.scm (texlive-font-maps): Check if TEXLIVE-SCRIPTS is present
    in the manifest before trying to generate font maps.
which was the last time the profile hook for font generation has been
touched.

Andreas




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