I am out of the office until Wednesday 11/09/2005.  Any computer related help 
should be directed to [EMAIL PROTECTED]

-Matt

>>> caret-users 10/26/05 12:51 >>>

Mike,

In addition to Donna's helpful comments regarding mapping of regional  
volume data to average fiducial surfaces, there are a couple of other  
ways to adjust colors that might prove useful.  One is the Attributes:  
Metric: Convert Metric to RGB paint file option.  Another is Surface:  
ROI: Operations:  Assign paint attributes to selected nodes.

Since this dialog now contains various items that may be of interest to  
others, I am copying this to the caret-users list.

David

On Oct 26, 2005, at 11:08 AM, Donna Hanlon wrote:

> Hi Mike,
>
> If nothing else, you could make sure your visualization spec has the  
> appropriate average fiducial surface in it; load the spec file and  
> make sure that fiducial was selected; and use the Map to Caret vs the  
> Map to Caret with Atlas option. (In fact, if you think you'll almost  
> always be using AFM vs MFM, then there's no advantage to the Map to  
> Caret with Atlas over the Map to Caret option, assuming you have the  
> correct average fiducial loaded.) Just remember to save the resulting  
> metric/paint, since I believe the Map to Caret function doesn't  
> generate an output file; it just loads the mapping in memory as a  
> metric/paint column, but disappears if you exit Caret without saving  
> as a metric/paint.
>
> If you go the paint route, the areacolor file (Attributes: Area Color,  
> http://brainmap.wustl.edu/caret/html/file_formats/ 
> file_formats.html#areaColor) controls the color mapping. If you go the  
> metric route, the palette file  
> (http://brainmap.wustl.edu/caret/html/file_formats/ 
> file_formats.html#paletteFile) controls the color mapping.
>
> Donna
>
> On 10/26/2005 10:57 AM, Mike Fox wrote:
>
>> Is there a way to map regional data to the average fiducial map? When  
>> I map functional data I appear to have this option, but not when I  
>> map regional data (with which AFM would be most useful).
>>
>> Alternatively, If I map regional data as functional data (ie data  
>> with discreet integer values) using AFM, is there a way to specify  
>> the color of each region. I'm currently using this approach and plan  
>> to try and change the colors of each region later using photoshop,  
>> but I figure there must be a way to do it in caret.
>>
>> Thanks,
>>
>> Mike
>>
>> Michael Fox
>>
>> Laboratory of Dr. Marcus Raichle
>>
>> Mallinckrodt Institute of Radiology
>>
>> Washington University in St. Louis
>>
>> Medical Scientist Training Program
>>
>> (314) 747-3073
>>
>> ---------------------------------------------------------------------- 
>> --
>>
>> *From:* David Van Essen [mailto:[EMAIL PROTECTED]
>> *Sent:* Friday, October 21, 2005 9:36 PM
>> *To:* Mike Fox
>> *Cc:* Donna Hanlon; David Van Essen
>> *Subject:* Re: visualization specs; MFM vs AFM
>>
>> Mike,
>>
>> On Oct 21, 2005, at 10:48 AM, Mike Fox wrote:
>>
>>     Dr. Van Essen,
>>
>>     Thanks for the spec files. I was having a tremendous amount of
>>     difficulty finding them on sums without your links.
>>
>> We are working to enhance our search capabilities, but obviously have  
>> quite a ways to go on this.
>>
>>     The question I had concerned the validity of mapping to 12
>>     individuals, then averaging those results, as compared to mapping
>>     just once to the average anatomy of the 12 individuals (a new
>>     function of caret). The two do not always give the same result,
>>     and I was wondering if you felt one was superior to the other and
>>     why. I know that volume space atlas registration has adopted the
>>     second approach (ie data is warped to a single atlas which is the
>>     average of multiple subjects anatomy), but this does not
>>     necessarily make it superior.
>>
>> For starters, it's useful to review what I said about this topic in  
>> the Discussion of the PALS paper:
>>
>> In order to interpret the results of MFM, it is important to consider  
>> several underlying assumptions. Without access to the individual  
>> structural and fMRI data in any given study, it is impossible to work  
>> backwards from volume-averaged group data to determine what the  
>> actual pattern would be in any individual. Hence, the activations  
>> seen on any of the individual PALS-B12 surfaces do not reflect a  
>> pattern in fact attributable to any of the actual fMRI subjects. Nor  
>> do they necessarily reflect the pattern that would have arisen in the  
>> 12 subjects whose structural data contributed to the atlas if they  
>> had been tested using the same fMRI paradigm. MFM does provide an  
>> objective strategy for estimating both the region of most likely  
>> activation and a plausible upper bound on the total extent of  
>> activation. This constitutes an important advance over the common  
>> current practice of mapping volume-averaged results onto a  
>> single-subject atlas.
>>
>> In many situations, it is appropriate to map group-average data using  
>> both AFM and MFM. The two mapping methods yield similar but not  
>> identical spatial patterns and are inherently complementary. AFM is  
>> conceptually simpler and allows readout of values at each surface  
>> node that correspond to a particular voxel value. MFM provides a more  
>> objective assessment of the most likely spatial distribution on the  
>> atlas surface.
>>
>> -----
>>
>> In short, I contend that MFM is a superior way to estimate the most  
>> likely spatial location of regions likely to have been modulated in  
>> any given paradigm. AFM can give significant biases in spatial  
>> localization, depending on the nature and location of the data.
>>
>> However, a price is paid in terms of relating the surface node values  
>> in an MFM map to the voxel values in the volume. In some situations  
>> that's pretty important, but in others it may be largely irrelevant.
>>
>> These issues are truly complex, as they are intimately linked to the  
>> nature of structural and functional variability and what is really  
>> meant by corresponding locations in different individual hemispheres.
>>
>> I hope this is helpful. If you have further comments, questions, or  
>> discussion points, let me know.
>>
>> David
>>


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