Hi!

I have been playing a bit more with the misalignment between the cortical surface and the MRI in the left hemisphere of the macaque data set released in January 2004. I have replaced the original HEAD files with the attached ones and I am relatively happy with the results. CAUTION: These files should only be applied to the left hemisphere, not to the right one!

Best,

Jochen.

David Van Essen wrote:
Jochen,

On Oct 13, 2005, at 6:50 PM, Jochen Ditterich wrote:

    Thank you, David. I probably have been using older files than the
    ones you have pointed me to, but there is one thing I don't
    understand. When I go to the SumsDB home page (without logging in,
    just public access), select the Atlases directory, and select the
    MACAQUE directory I basically have access to the following two
    files: MACAQUE.LEFT_HEM.04-01-29.tar.gz and
    MACAQUE.RIGHT_HEM.04-01-29.tar.gz. These are the files I have been
    working with and I have always assumed that these are the latest
    releases of the macaque data sets.


They were the latest back in January 2004, as indicated by the date in the filename. However, there are many more recent macaque atlas files in SumsDB.

One data set in particular is an updated right hemisphere macaque atlas; this should be the current starting point for getting data files of interest. This is the Macaque.F99UA1.Cerebral.RIGHT.ATLAS_SCENES.35946.spec: http://sumsdb.wustl.edu/sums/archivelist.do?archive_id=6413561 in the ROOT /public /ATLAS_DATA_SETS /MACAQUE/ directory. As the name indicates, it incorporates 'scene' files that facilitate viewing in both Caret and WebCaret.

    When searching for the newer files you have pointed me to
    individually I can find them. Is there a complete archive available
    like the ones I have been using so far containing all necessary
    files or do I have to download them separately and figure out which
    ones belong together?

Your questions are very sensible, and they point to the reality that we are still chipping away at getting our 'atlas house' in better order. Thus, we have a newer scenes-based atlas file for the macaque right hemisphere, but not yet one for the left. Basically, this is because we are multi-tasking on many atlas and other fronts; it is a challenge to keep the atlas datasets reasonably current for human, macaque, rat, and mouse in the face of software refinements along with additional data that is good to bring into the atlas framework.

Feedback from the user community helps us prioritize what aspects are most useful to concentrate on.

David


    David Van Essen wrote:

        Hi Jochen,
        On Oct 13, 2005, at 4:58 PM, Jochen Ditterich wrote:
        Hi Donna and John,
        I was running into a strange observation when using the "Surface
        Outline" function in Caret's MRI viewer. When applying it to your
        macaque cortex datasets there seems to be a relatively substantial
        misalignment between the MRI and the layer 4 surface model,
        especially for the left hemisphere. Have you noticed this before or
        am I doing something wrong?
        There are multiple versions of the macauqe fiducial surface and
        the volume data in SumsDB, and not all of them are properly
        aligned with one another.
        The relevant data files are accessible from the Atlases
        directory, along the top row of the SumsDB home page. Select the
        MACAQUE/ directory
        
(http://sumsdb.wustl.edu/sums/directory.do?dir_id=679531&dir_name=MACAQUE),
        then the hemisphere(s) you want. You can then view the data in
        WebCaret and download what you like.
        Alternatively, you can directly download the following two
        surfaces and one volume that should be well aligned:
        Macaque.F99UA1.LR.03-11+orig.HEAD
        http://sumsdb.wustl.edu:80/sums/archivelist.do?id=6413573
        Macaque.F99UA1.Cerebral.L.FIDUCIAL.AC_origin.34132.coord
        http://sumsdb.wustl.edu:80/sums/archivelist.do?id=685724
        Macaque.F99UA1.Cerebral.R.FIDUCIAL.AC_origin.04-01-23.35946.coord
        http://sumsdb.wustl.edu:80/sums/archivelist.do?id=686089
        I generated screen shots from a combination that is well
        aligned, but it got put on hold by the Caret 'moderator' because
        of image size. That version will presumably be distributed
        tomorrow, but in the meantime this is the text-only response.
        Let us know if alignment problems persist or if there are other
        issues that arise.
        David VE
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--
    -------------------------

    Jochen Ditterich, Ph.D.
    Assistant Professor
    Center for Neuroscience
    University of California
    1544 Newton Court
    Davis, CA 95616
    USA

    office: +1 (530) 754-5084
    lab: +1 (530) 754-6987
    fax: +1 (530) 757-8827
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--

-------------------------

Jochen Ditterich, Ph.D.
Assistant Professor
Center for Neuroscience
University of California
1544 Newton Court
Davis, CA 95616
USA

office: +1 (530) 754-5084
lab:    +1 (530) 754-6987
fax:    +1 (530) 757-8827
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