Brian,

Your question gets at the heart of the differences between AFM (average fiducial mapping) and MFM (multi-fiducial mapping), which is discussed in my 2005 Neuroimage paper.

In essence, the MFM value at a given node is the average of the value for the corresponding nodes in the 12 fiducial subjects, and the positions of these nodes is inherently variable. So the overall peak will typically be lower with MFM than AFM. (The exception would be if the average fiducial surface happened to miss the overall maximum in the volume, which is possible but seems not to occur often.) But it's not any simple linear transform.

The main advantage of MFM is that it gives you a better estimate of the location of the peak(s), and we recommend it if that is your main objective. If you need to hang onto the values of individual voxels, then AFM is better.

If you're in a position to do surface-based analysis of individual subjects, then spatial resolution improves substantially.

Hope this helps.

David

On Oct 9, 2007, at 6:54 PM, [EMAIL PROTECTED] wrote:



Caret folks-- I'm just starting to get acquainted with Caret and am enjoying the
program.

I've been mapping my zstat_thresh file from FSL onto: 1) the PALS brain, 2) the AVG fiducial map, and 3) the multifiducial maps. The images I get from 1 & 2
are
identical with the same Zmax (3.6) but #3 has a Zmax that is much lower (2.8). Is this supposed to happen? By playing with the Zmin on the display, it looks
like there's some linear transformation going on for #2 vs. #3.

thanks for any suggestions,
Brian
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