You might try the low threshold hindbrain removal, but don't get your
hopes too high.

How much did you shift the GMpeak?  This is definitely what I would have
tried, and if that failed, I'd try lowering the WMpeak (leaving the GMpeak
constant).

> Thank you, Donna!
>
> I have uploaded a bias-corrected version named
> "freckles_bias_corrected.zip" (using BrainSuite's BFC algorithm). After
> adjusting the peaks, the segmentation runs through, but the
> posteriormost parts of the cortex are always missing. I have tried a
> manual correction of the segmentation volume, but, while I am able to
> remove unwanted parts from the fiducial surface, I am apparently unable
> to add missing parts. Is this possible? If so, is there a special step
> involved other than selecting "Segmentation Volume Post Processing" and
> the manually corrected segmentation volume?
>
> In case it is not possible to add missing parts using a manual
> correction of the segmentation volume, is there anything else I can do?
> Shifting the grey matter peak in the appropriate direction for including
> the missing voxels makes the segmentation process fail.
>
> Best,
>
> Jochen
>
> On 4/5/2010 8:12 AM, Donna Dierker wrote:
>> Hi Jochen,
>>
>> I think your biggest problem was that your peaks were set too low.
>>
>> The MRI quality is not the best, and perhaps some nonuniformity
>> correction (e.g., FSL's fast) might improve your result further. But
>> your GM peak was set way too low. You histogram is somewhat misleading
>> (capture attached). If you set it at the peaks, the way you did, the
>> GMpeak will be way too low. See
>> http://brainvis.wustl.edu/help/peak_tweaking for more help on peaks.
>>
>> Try GMpeak=190, WMpeak=230 and see how you do. My results looked
>> reasonable (reasonable.jpg). In my case, though, the graph error
>> correction method cut off a lateral slab. Turning it off should restore
>> sanity (if not a few pesky handles).
>>
>> There were two issues with stereotactical_coord_AC_R.hdr:
>>
>> * The name suggests right hem, but the hem appeared to be a left hem
>> (left-right flipped?).
>>
>> * It was not centered near the AC, so the origin would need to be re-set
>> before you could hope to get any decent segmentation.
>>
>> Donna
>>
>> On 04/02/2010 01:20 PM, Jochen Ditterich wrote:
>>> Hi Donna and John,
>>>
>>> I am trying to segment a macaque brain and to flatten the cortex, but
>>> I haven't been able to make it through the segmentation process
>>> without error messages. I am not sure whether this is due to quality
>>> issues with the MRI or whether it has something to do with the
>>> implanted recording chambers. I have uploaded a file named
>>> "freckles.zip" that contains both the uncropped volume as well as the
>>> cropped volumes for the two hemispheres. Any feedback would be
>>> appreciated. Does anybody have experience segmenting MRIs taken from
>>> animals with implants?
>>>
>>> Thanks a lot,
>>>
>>> Jochen
>>>
>>> -------------------------
>>>
>>> Jochen Ditterich, Ph.D.
>>> Assistant Professor
>>> Center for Neuroscience
>>> University of California
>>> 1544 Newton Court
>>> Davis, CA 95618
>>> USA
>>>
>>> office: +1 (530) 754-5084
>>> lab: +1 (530) 754-6987
>>> fax: +1 (530) 757-8827
>>> _______________________________________________
>>> caret-users mailing list
>>> [email protected]
>>> http://brainvis.wustl.edu/mailman/listinfo/caret-users
>>
>>
>>
>> _______________________________________________
>> caret-users mailing list
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>
> --
>
> -------------------------
>
> Jochen Ditterich, Ph.D.
> Assistant Professor
> Center for Neuroscience
> University of California
> 1544 Newton Court
> Davis, CA 95618
> USA
>
> office: +1 (530) 754-5084
> lab:    +1 (530) 754-6987
> fax:    +1 (530) 757-8827
> _______________________________________________
> caret-users mailing list
> [email protected]
> http://brainvis.wustl.edu/mailman/listinfo/caret-users
>

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