Dear Matt,
Thank you for your reply to my question about myelin mapping.
There was indeed an issue with oblique s- and qforms (for the T2 images) which I resolved. I discovered for a subject however that still for frontal and occipital areas t1/t2 ratios were not well mapped (there are large areas that give values zero). Indeed, when I look at the volume-surface registration in Caret the areas do not correspond well.

I have several questions and would be very grateful if you could help me:

1. I wondered if for the original T1 the stereotaxic coordinates should be set to 0,0,0 for the anterior commissure before running myelin mapping.

2. Should the original T1 be set in LPI orientation before myelin mapping or is Caret doing this automatically? Might this be in conflict with Freesurfer files and how to proceed? And should the original T1 and T2 be skull-stripped?

3. In the myelin mapping operations it is indicated that images are best not resampled with trilinear interpolation. However, the mri_convert rl mri/rawavg.mgz mri/ribbon.mgz ribbon.nii.gz command is actually using trilinear interpolation. Is it possible and necessary to do mri_convert with spline interpolation?

Thank you very much for your suggestions!

Best,
Ruthger


Le 2014-03-15 18:00, [email protected] a écrit :
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Today's Topics:

   1. Re: question about myelin mapping (Matt Glasser)



----------------------------------------------------------------------

Message: 1
Date: Fri, 14 Mar 2014 11:42:29 -0500
From: Matt Glasser <[email protected]>
To: "Caret, SureFit, and SuMS software users"
        <[email protected]>
Subject: Re: [caret-users] question about myelin mapping
Message-ID: <cf489b8d.c23b3%[email protected]>
Content-Type: text/plain;       charset="ISO-8859-1"

Do the volumes align with the surfaces? Did you remove any oblique sforms?

Peace,

Matt.

On 3/14/14 8:01 AM, "Righart, Ruthger" <[email protected]> wrote:

Dear Caret experts,

I am using Caret for myelin mapping and I got first results for 4
subjects.
After loading MyelinMapping.metric in Caret, for some of the subjects
large areas are missing, both for left and right hemisphere,
particularly in the occipital areas (i.e., the metric file seems to have missing values, however the corrected thickness metric displays values
in these areas).

Registration of T2-to-T1 is fine. The ribbon.nii.gz file and the
T1wDividedByT2w_ribbon.nii.gz seem fine as well, though the ribbon in
the occipital areas has fewer voxels than other areas (probably because
these areas are relatively thin), and I wondered if this may cause a
problem for the final metric data.

The caret_command -myelin-mapping script reports rather high
percentages of missing nodes : ?Out of 113592 cortex nodes, 50.37% were zero and needed correction. When reconstructing discarded nodes, 68.88%
were zero and not used?.

Thank you very much in advance for your time, any help would be very
much appreciated!







Ruthger Righart

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